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Co-culture with mesenchymal stromal cells increases proliferation and maintenance of haematopoietic progenitor cells

Mesenchymal stromal cells (MSC) have been suggested to provide a suitable cellular environment for in vitro expansion of haematopoietic stem and progenitor cells (HPC) from umbilical cord blood. In this study, we have simultaneously analysed the cell division history and immunophenotypic differentia...

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Bibliographic Details
Main Authors: Walenda, Thomas (Author) , Bork, Simone (Author) , Horn, Patrick (Author) , Wein, Frederik (Author) , Saffrich, Rainer (Author) , Diehlmann, Anke (Author) , Eckstein, Volker (Author) , Ho, Anthony Dick (Author) , Wagner, Wolfgang (Author)
Format: Article (Journal)
Language:English
Published: 14 March 2010
In: Journal of cellular and molecular medicine
Year: 2010, Volume: 14, Issue: 1/2, Pages: 337-350
ISSN:1582-4934
DOI:10.1111/j.1582-4934.2009.00776.x
Online Access:Resolving-System, lizenzpflichtig, Volltext: https://doi.org/10.1111/j.1582-4934.2009.00776.x
Verlag, lizenzpflichtig, Volltext: https://onlinelibrary.wiley.com/doi/abs/10.1111/j.1582-4934.2009.00776.x
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Author Notes:Thomas Walenda, Simone Bork, Patrick Horn, Frederik Wein, Rainer Saffrich, Anke Diehlmann, Volker Eckstein, Anthony D. Ho, Wolfgang Wagner
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Summary:Mesenchymal stromal cells (MSC) have been suggested to provide a suitable cellular environment for in vitro expansion of haematopoietic stem and progenitor cells (HPC) from umbilical cord blood. In this study, we have simultaneously analysed the cell division history and immunophenotypic differentiation of HPC by using cell division tracking with carboxyfluorescein diacetate N-succinimidyl ester (CFSE). ...
Item Description:Gesehen am 28.09.2023
Physical Description:Online Resource
ISSN:1582-4934
DOI:10.1111/j.1582-4934.2009.00776.x

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