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A network medicine approach to study comorbidities in heart failure with preserved ejection fraction

Comorbidities are expected to impact the pathophysiology of heart failure (HF) with preserved ejection fraction (HFpEF). However, comorbidity profiles are usually reduced to a few comorbid disorders. Systems medicine approaches can model phenome-wide comorbidity profiles to improve our understanding...

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Main Authors: Lanzer, Jan David (Author) , Valdeolivas, Alberto (Author) , Pepin, Mark (Author) , Hund, Hauke (Author) , Backs, Johannes (Author) , Frey, Norbert (Author) , Friederich, Hans-Christoph (Author) , Schultz, Jobst-Hendrik (Author) , Sáez Rodríguez, Julio (Author) , Levinson, Rebecca T. (Author)
Format: Article (Journal)
Language:English
Published: 2023
In: BMC medicine
Year: 2023, Volume: 21, Pages: 1-21
ISSN:1741-7015
DOI:10.1186/s12916-023-02922-7
Online Access:Verlag, kostenfrei, Volltext: https://doi.org/10.1186/s12916-023-02922-7
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Author Notes:Jan D. Lanzer, Alberto Valdeolivas, Mark Pepin, Hauke Hund, Johannes Backs, Norbert Frey, Hans-Christoph Friederich, Jobst-Hendrik Schultz, Julio Saez-Rodriguez and Rebecca T. Levinson
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Summary:Comorbidities are expected to impact the pathophysiology of heart failure (HF) with preserved ejection fraction (HFpEF). However, comorbidity profiles are usually reduced to a few comorbid disorders. Systems medicine approaches can model phenome-wide comorbidity profiles to improve our understanding of HFpEF and infer associated genetic profiles.
Item Description:Veröffentlicht: 24. Juli 2023
Gesehen am 02.10.2023
Physical Description:Online Resource
ISSN:1741-7015
DOI:10.1186/s12916-023-02922-7

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