Influence of comorbidity with depression on interdisciplinary therapy: outcomes in patients with chronic low back pain

Our previous work showed higher tumour necrosis factor (TNF)-α levels in patients with chronic low back pain (cLBP) compared to healthy controls. However, patients with depression as a comorbidity did not have higher TNF-α levels in comparison to patients without depression. In this study we investi...

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Bibliographic Details
Main Authors: Wang, Haili (Author) , Ahrens, Carsten (Author) , Rief, Winfried (Author) , Schiltenwolf, Marcus (Author)
Format: Article (Journal)
Language:English
Published: 11 October 2010
In: Arthritis Research & Therapy
Year: 2010, Volume: 12, Issue: 5, Pages: 1-11
ISSN:1465-9913
DOI:10.1186/ar3155
Online Access:Resolving-System, kostenfrei, Volltext: https://doi.org/10.1186/ar3155
Verlag, kostenfrei, Volltext: https://arthritis-research.biomedcentral.com/articles/10.1186/ar3155
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Author Notes:Haili Wang, Carsten Ahrens, Winfried Rief, Marcus Schiltenwolf
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Summary:Our previous work showed higher tumour necrosis factor (TNF)-α levels in patients with chronic low back pain (cLBP) compared to healthy controls. However, patients with depression as a comorbidity did not have higher TNF-α levels in comparison to patients without depression. In this study we investigated the influence of depression on therapy outcomes such as TNF-α serum levels, pain intensity and back function in patients with cLBP. Our hypothesis was that patients with both cLBP and depression benefit no less than patients with cLBP alone from the multidisciplinary pain therapy.
Item Description:Gesehen am 10.10.2023
Physical Description:Online Resource
ISSN:1465-9913
DOI:10.1186/ar3155