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Impact of growth factors and PTHrP on early and late chondrogenic differentiation of human mesenchymal stem cells

Common in vitro protocols for chondrogenesis of mesenchymal stem cells (MSCs) induce an inadequate, hypertrophic differentiation cascade reminiscent of endochondral bone formation. We aimed to modify chondrogenic protocols in order to identify potent inducers, promotors, and inhibitors to achieve be...

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Bibliographic Details
Main Authors: Weiss, Stefan (Author) , Hennig, Thea (Author) , Bock, Rosalie (Author) , Steck, Eric (Author) , Richter, Wiltrud (Author)
Format: Article (Journal)
Language:English
Published: 4 January 2010
In: Journal of cellular physiology
Year: 2010, Volume: 223, Issue: 1, Pages: 84-93
ISSN:1097-4652
DOI:10.1002/jcp.22013
Online Access:Resolving-System, lizenzpflichtig, Volltext: https://doi.org/10.1002/jcp.22013
Verlag, lizenzpflichtig, Volltext: https://onlinelibrary.wiley.com/doi/abs/10.1002/jcp.22013
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Author Notes:S. Weiss, T. Hennig, R. Bock, E. Steck, and W. Richter
Description
Summary:Common in vitro protocols for chondrogenesis of mesenchymal stem cells (MSCs) induce an inadequate, hypertrophic differentiation cascade reminiscent of endochondral bone formation. We aimed to modify chondrogenic protocols in order to identify potent inducers, promotors, and inhibitors to achieve better chondrogenesis. ...
Item Description:Gesehen am 24.10.2023
Physical Description:Online Resource
ISSN:1097-4652
DOI:10.1002/jcp.22013

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