Head-to-head intra-individual comparison of biodistribution and tumor uptake of 68Ga-FAPI and 18F-FDG PET/CT in cancer patients

FAPI ligands (fibroblast activation protein inhibitor), a novel class of radiotracers for PET/CT imaging, demonstrated in previous studies rapid and high tumor uptake. The purpose of this study is the head-to-head intra-individual comparison of 68Ga-FAPI versus standard-of-care 18F-FDG in PET/CT in...

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Main Authors: Giesel, Frederik L. (Author) , Kratochwil, Clemens (Author) , Schlittenhardt, Joel (Author) , Dendl, Katharina (Author) , Eiber, Matthias (Author) , Staudinger, Fabian (Author) , Kessler, Lukas (Author) , Fendler, Wolfgang (Author) , Lindner, Thomas (Author) , Körber, Stefan A. (Author) , Cardinale, Jens (Author) , Sennung, David (Author) , Röhrich, Manuel (Author) , Debus, Jürgen (Author) , Sathekge, Mike (Author) , Haberkorn, Uwe (Author) , Calais, Jeremie (Author) , Serfling, Sebastian (Author) , Buck, Andreas L. (Author)
Format: Article (Journal)
Language:English
Published: 17 June 2021
In: European journal of nuclear medicine and molecular imaging
Year: 2021, Volume: 48, Issue: 13, Pages: 4377-4385
ISSN:1619-7089
DOI:10.1007/s00259-021-05307-1
Online Access:Verlag, kostenfrei, Volltext: https://doi.org/10.1007/s00259-021-05307-1
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Author Notes:Frederik L. Giesel, Clemens Kratochwil, Joel Schlittenhardt, Katharina Dendl, Matthias Eiber, Fabian Staudinger, Lukas Kessler, Wolfgang P. Fendler, Thomas Lindner, Stefan A. Koerber, Jens Cardinale, David Sennung, Manuel Roehrich, Juergen Debus, Mike Sathekge, Uwe Haberkorn, Jeremie Calais, Sebastian Serfling, Andreas L. Buck
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Summary:FAPI ligands (fibroblast activation protein inhibitor), a novel class of radiotracers for PET/CT imaging, demonstrated in previous studies rapid and high tumor uptake. The purpose of this study is the head-to-head intra-individual comparison of 68Ga-FAPI versus standard-of-care 18F-FDG in PET/CT in organ biodistribution and tumor uptake in patients with various cancers.
Item Description:Im Titel sind die Zahlen 68 und 18 jeweils hochgestellt
Gesehen am 31.10.2023
Physical Description:Online Resource
ISSN:1619-7089
DOI:10.1007/s00259-021-05307-1