Life-threatening infection with multiresistant Staphylococcus epidermidis in a patient with end-stage renal disease: cure with chloramphenicol and quinupristin/dalfopristin (RP 59500)

A 45-year-old man with end-stage renal disease underwent a cadaveric kidney transplantation. The allograft had to be removed 10 days after transplantation because of an acute vascular rejection. After explantation, the patient suffered from a life-threatening infection with Staphylococcus epidermidi...

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Bibliographic Details
Main Authors: Mündlein, Eckehard (Author) , Baum, Heike von (Author) , Geiss, Heinrich K. (Author) , Springsklee, M. (Author) , Zeier, Martin (Author) , Andrassy, Konrad (Author)
Format: Article (Journal)
Language:English
Published: 1997
In: Infection
Year: 1997, Volume: 25, Issue: 4, Pages: 252-254
ISSN:1439-0973
DOI:10.1007/BF01713157
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1007/BF01713157
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Author Notes:E. Mündlein, H. von Baum, H.K. Geiss, M. Springsklee, M. Zeier, K. Andrassy
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Summary:A 45-year-old man with end-stage renal disease underwent a cadaveric kidney transplantation. The allograft had to be removed 10 days after transplantation because of an acute vascular rejection. After explantation, the patient suffered from a life-threatening infection with Staphylococcus epidermidis involving lungs, eyes and liver for 11 months. Despite adequate therapy including vancomycin followed by teicoplanin, he developed spondylodiscitis requiring repeated surgical interventions. The definitive cure was achieved by a sequential therapy with chloramphenicol and quinupristin/dalfopristin.
Item Description:Gesehen am 02.11.2023
Physical Description:Online Resource
ISSN:1439-0973
DOI:10.1007/BF01713157