Cover Image

Meningeal involvement in Wegener's granulomatosis confirmed and monitored by positive circulating antineutrophil cytoplasm in cerebrospinal fluid

MRI and CSF investigations revealed meningeal involvement in a 29-year-old patient with biopsy-confirmed Wegener's granulomatosis. The intracranial manifestation of Wegener's granulomatosis was supported by the detection of pathologic circulating antineutrophil cytoplasm (c-ANCA) in the CS...

Full description

Saved in:
Bibliographic Details
Main Authors: Spranger, Matthias (Author) , Schwab, Stefan (Author) , Meinck, Hans-Michael (Author) , Tischendorf, Matthias (Author) , Sis, Jeanne (Author) , Breitbart, Andreas (Author) , Andrassy, Konrad (Author)
Format: Article (Journal)
Language:English
Published: January 1, 1997
In: Neurology
Year: 1997, Volume: 48, Issue: 1, Pages: 263-265
ISSN:1526-632X
DOI:10.1212/WNL.48.1.263
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1212/WNL.48.1.263
Verlag, lizenzpflichtig, Volltext: https://n.neurology.org/content/48/1/263
Get full text
Author Notes:M. Spranger, S. Schwab, H.-M. Meinck, M. Tischendorf, J. Sis, A. Breitbart, K. Andrassy
Description
Summary:MRI and CSF investigations revealed meningeal involvement in a 29-year-old patient with biopsy-confirmed Wegener's granulomatosis. The intracranial manifestation of Wegener's granulomatosis was supported by the detection of pathologic circulating antineutrophil cytoplasm (c-ANCA) in the CSF. We monitored disease activity by c-ANCA measurement in the CSF. After repeated cycles of intrathecal administration of methotrexate and corticoids, progression of meningeal infiltration stopped, and CSF c-ANCA titers became negative. - NEUROLOGY 1997;48: 263-265
Item Description:Gesehen am 02.11.2023
Physical Description:Online Resource
ISSN:1526-632X
DOI:10.1212/WNL.48.1.263

Similar Items