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Prognosis and management of acute symptomatic seizures: a prospective, multicenter, observational study

Acute symptomatic epileptic seizures are frequently seen in neurocritical care. To prevent subsequent unprovoked seizures, long-term treatments with antiseizure medications are often initiated although supporting evidence is lacking. This study aimed at prospectively assessing the risk of unprovoked...

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Main Authors: Herzig-Nichtweiß, Julia (Author) , Salih, Farid (Author) , Berning, Sascha (Author) , Malter, Michael P. (Author) , Pelz, Johann O. (Author) , Lochner, Piergiorgio (Author) , Wittstock, Matthias (Author) , Günther, Albrecht (Author) , Alonso, Angelika (Author) , Fuhrer, Hannah (Author) , Schönenberger, Silvia (Author) , Petersen, Martina (Author) , Kohle, Felix (Author) , Müller, Annekatrin (Author) , Gawlitza, Alexander (Author) , Gubarev, Waldemar (Author) , Holtkamp, Martin (Author) , Vorderwülbecke, Bernd J. (Author)
Format: Article (Journal)
Language:English
Published: 2023
In: Annals of intensive care
Year: 2023, Volume: 13, Pages: 1-14
ISSN:2110-5820
DOI:10.1186/s13613-023-01183-0
Online Access:Verlag, kostenfrei, Volltext: https://doi.org/10.1186/s13613-023-01183-0
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Author Notes:Julia Herzig-Nichtweiß, Farid Salih, Sascha Berning, Michael P. Malter, Johann O. Pelz, Piergiorgio Lochner, Matthias Wittstock, Albrecht Günther, Angelika Alonso, Hannah Fuhrer, Silvia Schönenberger, Martina Petersen, Felix Kohle, Annekatrin Müller, Alexander Gawlitza, Waldemar Gubarev, Martin Holtkamp, Bernd J. Vorderwülbecke and IGNITE! study group
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Summary:Acute symptomatic epileptic seizures are frequently seen in neurocritical care. To prevent subsequent unprovoked seizures, long-term treatments with antiseizure medications are often initiated although supporting evidence is lacking. This study aimed at prospectively assessing the risk of unprovoked seizure relapse with respect to the use of antiseizure medications. It was hypothesized that after a first acute symptomatic seizure of structural etiology, the cumulative 12-month risk of unprovoked seizure relapse is ≤ 25%.
Item Description:Veröffentlicht: 15. September 2023
Gesehen am 13.11.2023
Physical Description:Online Resource
ISSN:2110-5820
DOI:10.1186/s13613-023-01183-0

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