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An efficient one-pot synthesis of tetra-substituted pyrroles

The three-component reaction of primary amines, dialkyl acetylenedicarboxylates and β-nitrostyrene derivatives in the presence of Iron(III) chloride afforded 1,2,3,4-tetra-substituted pyrroles in high yields. These reactions could precede via domino Michael addition/cyclization process.

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Bibliographic Details
Main Authors: Ghabraie, Elmira (Author) , Balalaie, Saeed (Author) , Bararjanian, Morteza (Author) , Bijanzadeh, Hamid Reza (Author) , Rominger, Frank (Author)
Format: Article (Journal)
Language:English
Published: 25 May 2011
In: Tetrahedron
Year: 2011, Volume: 67, Issue: 30, Pages: 5415-5420
ISSN:1464-5416
DOI:10.1016/j.tet.2011.05.076
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1016/j.tet.2011.05.076
Verlag, lizenzpflichtig, Volltext: https://www.sciencedirect.com/science/article/pii/S0040402011007502
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Author Notes:Elmira Ghabraie, Saeed Balalaie, Morteza Bararjanian, Hamid Reza Bijanzadeh, Frank Rominger
Description
Summary:The three-component reaction of primary amines, dialkyl acetylenedicarboxylates and β-nitrostyrene derivatives in the presence of Iron(III) chloride afforded 1,2,3,4-tetra-substituted pyrroles in high yields. These reactions could precede via domino Michael addition/cyclization process.
Item Description:Gesehen am 15.11.2023
Physical Description:Online Resource
ISSN:1464-5416
DOI:10.1016/j.tet.2011.05.076

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