DNA adducts in urothelial cells: relationship with biomarkers of exposure to arylamines and polycyclic aromatic hydrocarbons from tobacco smoke
Markers of exposure to polycyclic aromatic hydrocarbons (urinary 1-hydroxypyrene-glucuronide) and aromatic amines (4-aminobiphenyl-hemoglobin adducts), as well as urinary mutagenicity, were measured in 47 healthy smokers and 50 non-smokers. DNA adducts were determined by P32-postlabeling in the exfo...
Gespeichert in:
| Hauptverfasser: | , , , , , , |
|---|---|
| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
26 January 1996
|
| In: |
International journal of cancer
Year: 1996, Jahrgang: 65, Heft: 3, Pages: 314-316 |
| ISSN: | 1097-0215 |
| DOI: | 10.1002/(SICI)1097-0215(19960126)65:3<314::AID-IJC6>3.0.CO;2-2 |
| Online-Zugang: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1002/(SICI)1097-0215(19960126)65:3<314::AID-IJC6>3.0.CO;2-2 Verlag, lizenzpflichtig, Volltext: https://onlinelibrary.wiley.com/doi/abs/10.1002/%28SICI%291097-0215%2819960126%2965%3A3%3C314%3A%3AAID-IJC6%3E3.0.CO%3B2-2 
|
| Verfasserangaben: | Paolo Vineis, Glenn Talaska, Christian Malaveille, Helmut Bartsch, Tiziana Martone, Pornchai Sithisarankul, Paul Strickland |
MARC
| LEADER | 00000caa a2200000 c 4500 | ||
|---|---|---|---|
| 001 | 1877497665 | ||
| 003 | DE-627 | ||
| 005 | 20240311152000.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 240109s1996 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1002/(SICI)1097-0215(19960126)65:3<314::AID-IJC6>3.0.CO;2-2 |2 doi | |
| 035 | |a (DE-627)1877497665 | ||
| 035 | |a (DE-599)KXP1877497665 | ||
| 035 | |a (OCoLC)1425891737 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rda | ||
| 041 | |a eng | ||
| 084 | |a 33 |2 sdnb | ||
| 100 | 1 | |a Vineis, Paolo |e VerfasserIn |0 (DE-588)1219322423 |0 (DE-627)1735266434 |4 aut | |
| 245 | 1 | 0 | |a DNA adducts in urothelial cells |b relationship with biomarkers of exposure to arylamines and polycyclic aromatic hydrocarbons from tobacco smoke |c Paolo Vineis, Glenn Talaska, Christian Malaveille, Helmut Bartsch, Tiziana Martone, Pornchai Sithisarankul, Paul Strickland |
| 264 | 1 | |c 26 January 1996 | |
| 300 | |a 3 | ||
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Gesehen am 09.01.2024 | ||
| 520 | |a Markers of exposure to polycyclic aromatic hydrocarbons (urinary 1-hydroxypyrene-glucuronide) and aromatic amines (4-aminobiphenyl-hemoglobin adducts), as well as urinary mutagenicity, were measured in 47 healthy smokers and 50 non-smokers. DNA adducts were determined by P32-postlabeling in the exfoliated bladder cells of 39 healthy subjects. Both 1-hydroxypyrene-glucuronide (1-OHPG) and 4-aminobiphenyl adducts (4-ABP-Hb) were associated with smoking habits, but only 4-ABP-Hb adducts were associated with consumption of black, air-cured tobacco. The levels of 2 DNA adducts (numbers 2 and 4) in urothelial cells were clearly associated with 4-ABP-Hb adducts, in all subjects and in smokers. Levels of one of these DNA adducts (number 2) were also associated with 1-hydroxypyrene-glucuronide in urines, but in smokers the association was not statistically significant. Overall, these observations constitute further evidence of a role of arylamines in tobacco-induced bladder cancer. © 1996 Wiley-Liss, Inc. | ||
| 700 | 1 | |a Talaska, Glenn |e VerfasserIn |4 aut | |
| 700 | 1 | |a Malaveille, Christian |e VerfasserIn |4 aut | |
| 700 | 1 | |a Bartsch, Helmut |d 1940- |e VerfasserIn |0 (DE-588)1021102032 |0 (DE-627)691457018 |0 (DE-576)362545545 |4 aut | |
| 700 | 1 | |a Martone, Tiziana |e VerfasserIn |4 aut | |
| 700 | 1 | |a Sithisarankul, Pornchai |e VerfasserIn |4 aut | |
| 700 | 1 | |a Strickland, Paul |e VerfasserIn |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t International journal of cancer |d Bognor Regis : Wiley-Liss, 1966 |g 65(1996), 3, Seite 314-316 |h Online-Ressource |w (DE-627)269532781 |w (DE-600)1474822-8 |w (DE-576)079876129 |x 1097-0215 |7 nnas |a DNA adducts in urothelial cells relationship with biomarkers of exposure to arylamines and polycyclic aromatic hydrocarbons from tobacco smoke |
| 773 | 1 | 8 | |g volume:65 |g year:1996 |g number:3 |g pages:314-316 |g extent:3 |a DNA adducts in urothelial cells relationship with biomarkers of exposure to arylamines and polycyclic aromatic hydrocarbons from tobacco smoke |
| 856 | 4 | 0 | |u https://doi.org/10.1002/(SICI)1097-0215(19960126)65:3<314::AID-IJC6>3.0.CO;2-2 |x Verlag |x Resolving-System |z lizenzpflichtig |3 Volltext |
| 856 | 4 | 0 | |u https://onlinelibrary.wiley.com/doi/abs/10.1002/%28SICI%291097-0215%2819960126%2965%3A3%3C314%3A%3AAID-IJC6%3E3.0.CO%3B2-2 |x Verlag |z lizenzpflichtig |3 Volltext |
| 951 | |a AR | ||
| 992 | |a 20240109 | ||
| 993 | |a Article | ||
| 994 | |a 1996 | ||
| 998 | |g 1021102032 |a Bartsch, Helmut |m 1021102032:Bartsch, Helmut |d 50000 |e 50000PB1021102032 |k 0/50000/ |p 4 | ||
| 999 | |a KXP-PPN1877497665 |e 4451586852 | ||
| BIB | |a Y | ||
| SER | |a journal | ||
| JSO | |a {"type":{"bibl":"article-journal","media":"Online-Ressource"},"note":["Gesehen am 09.01.2024"],"language":["eng"],"recId":"1877497665","title":[{"title":"DNA adducts in urothelial cells","subtitle":"relationship with biomarkers of exposure to arylamines and polycyclic aromatic hydrocarbons from tobacco smoke","title_sort":"DNA adducts in urothelial cells"}],"person":[{"role":"aut","roleDisplay":"VerfasserIn","display":"Vineis, Paolo","given":"Paolo","family":"Vineis"},{"given":"Glenn","family":"Talaska","role":"aut","roleDisplay":"VerfasserIn","display":"Talaska, Glenn"},{"family":"Malaveille","given":"Christian","display":"Malaveille, Christian","roleDisplay":"VerfasserIn","role":"aut"},{"role":"aut","roleDisplay":"VerfasserIn","display":"Bartsch, Helmut","given":"Helmut","family":"Bartsch"},{"role":"aut","roleDisplay":"VerfasserIn","display":"Martone, Tiziana","given":"Tiziana","family":"Martone"},{"role":"aut","display":"Sithisarankul, Pornchai","roleDisplay":"VerfasserIn","given":"Pornchai","family":"Sithisarankul"},{"display":"Strickland, Paul","roleDisplay":"VerfasserIn","role":"aut","family":"Strickland","given":"Paul"}],"physDesc":[{"extent":"3 S."}],"relHost":[{"disp":"DNA adducts in urothelial cells relationship with biomarkers of exposure to arylamines and polycyclic aromatic hydrocarbons from tobacco smokeInternational journal of cancer","note":["Gesehen am 28.02.08","Darin: Predictive oncology"],"type":{"media":"Online-Ressource","bibl":"periodical"},"recId":"269532781","language":["eng"],"corporate":[{"role":"isb","roleDisplay":"Herausgebendes Organ","display":"International Union against Cancer"}],"pubHistory":["1.1966 -"],"titleTranslated":[{"translated":"Journal international du cancer"}],"part":{"text":"65(1996), 3, Seite 314-316","volume":"65","extent":"3","year":"1996","pages":"314-316","issue":"3"},"titleAlt":[{"title":"Predictive oncology"}],"title":[{"title_sort":"International journal of cancer","subtitle":"publication of the International Union against Cancer (UICC) = Journal international du cancer","title":"International journal of cancer"}],"physDesc":[{"extent":"Online-Ressource"}],"origin":[{"dateIssuedKey":"1966","publisher":"Wiley-Liss","dateIssuedDisp":"1966-","publisherPlace":"Bognor Regis"}],"id":{"eki":["269532781"],"doi":["10.1002/(ISSN)1097-0215"],"zdb":["1474822-8"],"issn":["1097-0215"]}}],"origin":[{"dateIssuedKey":"1996","dateIssuedDisp":"26 January 1996"}],"id":{"doi":["10.1002/(SICI)1097-0215(19960126)65:3<314::AID-IJC6>3.0.CO;2-2"],"eki":["1877497665"]},"name":{"displayForm":["Paolo Vineis, Glenn Talaska, Christian Malaveille, Helmut Bartsch, Tiziana Martone, Pornchai Sithisarankul, Paul Strickland"]}} | ||
| SRT | |a VINEISPAOLDNAADDUCTS2619 | ||