Inhaled nitric oxide for high-altitude pulmonary edema
High-altitude pulmonary edema is a life-threatening condition1 characterized by marked pulmonary vasoconstriction.2-6 Even though the exact underlying mechanisms of high-altitude pulmonary edema are incompletely understood, pulmonary hypertension is thought to play an important part.3,7-9 On the bas...
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| Main Authors: | , , , , , , , , , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
March 7, 1996
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| In: |
The New England journal of medicine
Year: 1996, Volume: 334, Issue: 10, Pages: 624-630 |
| ISSN: | 1533-4406 |
| DOI: | 10.1056/NEJM199603073341003 |
| Online Access: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1056/NEJM199603073341003
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| Author Notes: | Urs Scherrer, Laurent Vollenweider, Alain Delabays, Milos Savcic, Urs Eichenberger, Gian-Reto Kleger, Antonin Fikrle, Peter E. Ballmer, Pascal Nicod, Peter Bärtsch |
| Summary: | High-altitude pulmonary edema is a life-threatening condition1 characterized by marked pulmonary vasoconstriction.2-6 Even though the exact underlying mechanisms of high-altitude pulmonary edema are incompletely understood, pulmonary hypertension is thought to play an important part.3,7-9 On the basis of the hypothesis that in this condition pulmonary arteriolar vasoconstriction is heterogeneous, leading to areas of hypoperfusion and hyperperfusion, a decrease in pulmonary-artery pressure may be beneficial in two ways. A reduction of capillary pressure in overperfused areas may reduce the formation of edema, whereas augmentation of perfusion in previously underperfused areas, where gas exchange is not impaired, may improve . . . |
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| Item Description: | Gesehen am 17.01.2024 |
| Physical Description: | Online Resource |
| ISSN: | 1533-4406 |
| DOI: | 10.1056/NEJM199603073341003 |