Balanced activation of coagulation and fibrinolysis after a 2-h triathlon
To examine whether exercise-induced thrombin formation is accompanied by increased in vivo plasmin formation, we measured molecular markers and neoantigens of the hemostatic system in 10 male subjects (mean 29 yr, range 19-38) before, immediately after, and 2, 8, and 21 h after a triathlon lasting 1...
Gespeichert in:
| Hauptverfasser: | , , , , , |
|---|---|
| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
November 1995
|
| In: |
Medicine and science in sports and exercise
Year: 1995, Jahrgang: 27, Heft: 11, Pages: 1465-1470 |
| ISSN: | 1530-0315 |
| Online-Zugang: | Verlag, lizenzpflichtig, Volltext: https://journals.lww.com/acsm-msse/abstract/1995/11000/balanced_activation_of_coagulation_and.1.aspx Verlag, lizenzpflichtig, Volltext: https://pubmed.ncbi.nlm.nih.gov/8587481/ 
|
| Verfasserangaben: | Peter Bärtsch, Bärbel Welsch, Michael Albert, Birgit Friedmann, Marcel Levi, Egbert K.O. Kruithof |
MARC
| LEADER | 00000caa a2200000 c 4500 | ||
|---|---|---|---|
| 001 | 1879983427 | ||
| 003 | DE-627 | ||
| 005 | 20240311155638.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 240205s1995 xx |||||o 00| ||eng c | ||
| 035 | |a (DE-627)1879983427 | ||
| 035 | |a (DE-599)KXP1879983427 | ||
| 035 | |a (OCoLC)1425892592 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rda | ||
| 041 | |a eng | ||
| 084 | |a 33 |2 sdnb | ||
| 100 | 1 | |a Bärtsch, Peter |e VerfasserIn |0 (DE-588)1068984023 |0 (DE-627)821117483 |0 (DE-576)428341179 |4 aut | |
| 245 | 1 | 0 | |a Balanced activation of coagulation and fibrinolysis after a 2-h triathlon |c Peter Bärtsch, Bärbel Welsch, Michael Albert, Birgit Friedmann, Marcel Levi, Egbert K.O. Kruithof |
| 264 | 1 | |c November 1995 | |
| 300 | |a 6 | ||
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Gesehen am 05.02.2024 | ||
| 520 | |a To examine whether exercise-induced thrombin formation is accompanied by increased in vivo plasmin formation, we measured molecular markers and neoantigens of the hemostatic system in 10 male subjects (mean 29 yr, range 19-38) before, immediately after, and 2, 8, and 21 h after a triathlon lasting 128-163 min. Thrombin-antithrombin (TAT) complexes, fibrinopeptide A (FPA), and tissue plasminogen activator (t-PA) antigen were maximally increased immediately after exercise and decreased thereafter rapidly. Prothrombin fragment 1+2 (PTF1+2), fibrin degradation products (FbDP) and plasmin-antiplasmin (PAP) complexes rose to a similar extent 0 and 2 h after exercise and decreased thereafter. The maximal levels of PTF1 + 2, TAT, FPA, and FbDP were 1.5-, 2.1-, 1.8-, and 1.9-fold above baseline values, respectively, while t-PA antigen and PAP rose 9.9− and 10.6-fold above baseline, respectively. This investigation shows that strenuous prolonged exercise leads to a moderate activation of blood coagulation resulting in thrombin and fibrin formation which is accompanied by a greatly enhanced plasmin generation. It is concluded that the hemostatic system of healthy individuals is well kept in balance when stimulated by prolonged strenuous exercise. | ||
| 700 | 1 | |a Welsch, Bärbel |e VerfasserIn |0 (DE-588)112258251X |0 (DE-627)875739644 |0 (DE-576)175909431 |4 aut | |
| 700 | 1 | |a Albert, Michael |d 1963- |e VerfasserIn |0 (DE-588)128711523 |0 (DE-627)378308661 |0 (DE-576)297293257 |4 aut | |
| 700 | 1 | |a Friedmann-Bette, Birgit |d 1960- |e VerfasserIn |0 (DE-588)112694195 |0 (DE-627)519225937 |0 (DE-576)289739683 |4 aut | |
| 700 | 1 | |a Levi, Marcel |e VerfasserIn |4 aut | |
| 700 | 1 | |a Kruithof, Egbert K. O. |e VerfasserIn |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Medicine and science in sports and exercise |d Philadelphia, Pa. : Lippincott Williams & Wilkins, 1980 |g 27(1995), 11 vom: Nov., Seite 1465-1470 |h Online-Ressource |w (DE-627)324825846 |w (DE-600)2031167-9 |w (DE-576)094449503 |x 1530-0315 |7 nnas |a Balanced activation of coagulation and fibrinolysis after a 2-h triathlon |
| 773 | 1 | 8 | |g volume:27 |g year:1995 |g number:11 |g month:11 |g pages:1465-1470 |g extent:6 |a Balanced activation of coagulation and fibrinolysis after a 2-h triathlon |
| 856 | 4 | 0 | |u https://journals.lww.com/acsm-msse/abstract/1995/11000/balanced_activation_of_coagulation_and.1.aspx |x Verlag |z lizenzpflichtig |3 Volltext |
| 856 | 4 | 0 | |u https://pubmed.ncbi.nlm.nih.gov/8587481/ |x Verlag |z lizenzpflichtig |3 Volltext |
| 951 | |a AR | ||
| 992 | |a 20240205 | ||
| 993 | |a Article | ||
| 994 | |a 1995 | ||
| 998 | |g 112694195 |a Friedmann-Bette, Birgit |m 112694195:Friedmann-Bette, Birgit |d 910000 |d 910100 |e 910000PF112694195 |e 910100PF112694195 |k 0/910000/ |k 1/910000/910100/ |p 4 | ||
| 998 | |g 128711523 |a Albert, Michael |m 128711523:Albert, Michael |d 50000 |e 50000PA128711523 |k 0/50000/ |p 3 | ||
| 998 | |g 112258251X |a Welsch, Bärbel |m 112258251X:Welsch, Bärbel |d 50000 |e 50000PW112258251X |k 0/50000/ |p 2 | ||
| 998 | |g 1068984023 |a Bärtsch, Peter |m 1068984023:Bärtsch, Peter |d 910000 |d 910100 |e 910000PB1068984023 |e 910100PB1068984023 |k 0/910000/ |k 1/910000/910100/ |p 1 |x j | ||
| 999 | |a KXP-PPN1879983427 |e 4476520774 | ||
| BIB | |a Y | ||
| SER | |a journal | ||
| JSO | |a {"recId":"1879983427","physDesc":[{"extent":"6 S."}],"language":["eng"],"name":{"displayForm":["Peter Bärtsch, Bärbel Welsch, Michael Albert, Birgit Friedmann, Marcel Levi, Egbert K.O. Kruithof"]},"id":{"eki":["1879983427"]},"origin":[{"dateIssuedKey":"1995","dateIssuedDisp":"November 1995"}],"person":[{"family":"Bärtsch","role":"aut","display":"Bärtsch, Peter","given":"Peter"},{"family":"Welsch","display":"Welsch, Bärbel","role":"aut","given":"Bärbel"},{"given":"Michael","display":"Albert, Michael","role":"aut","family":"Albert"},{"given":"Birgit","display":"Friedmann-Bette, Birgit","role":"aut","family":"Friedmann-Bette"},{"display":"Levi, Marcel","role":"aut","family":"Levi","given":"Marcel"},{"family":"Kruithof","display":"Kruithof, Egbert K. O.","role":"aut","given":"Egbert K. O."}],"title":[{"title":"Balanced activation of coagulation and fibrinolysis after a 2-h triathlon","title_sort":"Balanced activation of coagulation and fibrinolysis after a 2-h triathlon"}],"relHost":[{"note":["Gesehen am 20.08.25"],"type":{"media":"Online-Ressource","bibl":"periodical"},"pubHistory":["Volume 12, issue 1 (1980)-"],"titleAlt":[{"title":"MSSE"}],"title":[{"title":"Medicine and science in sports and exercise","title_sort":"Medicine and science in sports and exercise","subtitle":"MSSE : official journal of the American College of Sports Medicine"}],"origin":[{"dateIssuedDisp":"1980-","publisherPlace":"Philadelphia, Pa. ; [Erscheinungsort nicht ermittelbar]","publisher":"Lippincott Williams & Wilkins ; Ovid","dateIssuedKey":"1980"}],"corporate":[{"role":"isb","display":"American College of Sports Medicine"}],"id":{"zdb":["2031167-9"],"eki":["324825846"],"issn":["1530-0315"]},"recId":"324825846","disp":"Balanced activation of coagulation and fibrinolysis after a 2-h triathlonMedicine and science in sports and exercise","part":{"pages":"1465-1470","volume":"27","extent":"6","year":"1995","text":"27(1995), 11 vom: Nov., Seite 1465-1470","issue":"11"},"physDesc":[{"extent":"Online-Ressource"}],"language":["eng"]}],"type":{"bibl":"article-journal","media":"Online-Ressource"},"note":["Gesehen am 05.02.2024"]} | ||
| SRT | |a BAERTSCHPEBALANCEDAC1995 | ||