HPV-associated head and neck cancer is characterized by distinct profiles of CD8+ T cells and myeloid-derived suppressor cells

Patients with HPV−-localized head and neck cancer (HNC) show inferior outcomes after surgery and radiochemotherapy compared to HPV-associated cancers. The underlying mechanisms remain elusive, but differences in immune status and immune activity may be implicated. In this study, we analyzed immune p...

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Autores principales:	Kansy, Benjamin Alexander (Autor) , Wehrs, Tim P. (Autor) , Bruderek, Kirsten (Autor) , Si, Yu (Autor) , Ludwig, Sonja (Autor) , Droege, Freya (Autor) , Haßkamp, Pia (Autor) , Henkel, Uta (Autor) , Dominas, Nina Tatjana Maria (Autor) , Hoffmann, Thomas K. (Autor) , Horn, Peter A. (Autor) , Schuler, Martin (Autor) , Gauler, Thomas C. (Autor) , Lindemann, Monika (Autor) , Lang, Stephan (Autor) , Bánkfalvi, Ágnes (Autor) , Brandau, Sven (Autor)
Formato:	Article (Journal)
Lenguaje:	inglés
Publicado:	29 November 2023
In:	Cancer immunology immunotherapy Year: 2023, Volumen: 72, Número: 12, Pages: 4367-4383
ISSN:	1432-0851
DOI:	10.1007/s00262-023-03571-8
Acceso en línea:	Verlag, kostenfrei, Volltext: https://doi.org/10.1007/s00262-023-03571-8
Notas de Autor:	Benjamin A. Kansy, Tim P. Wehrs, Kirsten Bruderek, Yu Si, Sonja Ludwig, Freya Droege, Pia Hasskamp, Uta Henkel, Nina Dominas, Thomas K. Hoffmann, Peter A. Horn, Martin Schuler, Thomas C. Gauler, Monika Lindemann, Stephan Lang, Agnes Bankfalvi, Sven Brandau