Alpha-1-antitrypsin-deficiency is associated with lower cardiovascular risk: an approach based on federated learning

Chronic obstructive pulmonary disease (COPD) is an inflammatory multisystemic disease caused by environmental exposures and/or genetic factors. Inherited alpha-1-antitrypsin deficiency (AATD) is one of the best recognized genetic factors increasing the risk for an early onset COPD with emphysema. Th...

Full description

Bibliographic Details

Main Authors:	Zöller, Daniela (Author) , Haverkamp, Lars Christian Arndt Simon (Author) , Makoudjou, Adeline (Author) , Sofack, Ghislain (Author) , Kiefer, Saskia (Author) , Gebele, Denis (Author) , Pfaffenlehner, Michelle (Author) , Boeker, Martin (Author) , Binder, Harald (Author) , Karki, Kapil (Author) , Seidemann, Christian (Author) , Schmeck, Bernd (Author) , Greulich, Timm (Author) , Renz, Harald (Author) , Schild, Stefanie (Author) , Seuchter, Susanne A. (Author) , Tibyampansha, Dativa (Author) , Buhl, Roland (Author) , Rohde, Gernot Gerhard Ulrich (Author) , Trudzinski, Franziska (Author) , Bals, Robert (Author) , Janciauskiene, Sabina (Author) , Stolz, Daiana (Author) , Fähndrich, Sebastian Wolfgang (Author)
Format:	Article (Journal)
Language:	English
Published:	18 January 2024
In:	Respiratory research Year: 2024, Volume: 25, Issue: 1, Pages: 1-10
ISSN:	1465-993X
DOI:	10.1186/s12931-023-02607-y
Online Access:	Verlag, kostenfrei, Volltext: https://doi.org/10.1186/s12931-023-02607-y Verlag, kostenfrei, Volltext: https://respiratory-research.biomedcentral.com/articles/10.1186/s12931-023-02607-y
Author Notes:	Daniela Zöller, Christian Haverkamp, Adeline Makoudjou, Ghislain Sofack, Saskia Kiefer, Denis Gebele, Michelle Pfaffenlehner, Martin Boeker, Harald Binder, Kapil Karki, Christian Seidemann, Bernd Schmeck, Timm Greulich, Harald Renz, Stefanie Schild, Susanne A. Seuchter, Dativa Tibyampansha, Roland Buhl, Gernot Rohde, Franziska C. Trudzinski, Robert Bals, Sabina Janciauskiene, Daiana Stolz and Sebastian Fähndrich