Emergence of carbapenem-resistant ST131 Escherichia coli carrying blaOXA-244 in Germany, 2019 to 2020

The dissemination of carbapenem-producing Gram-negative bacteria is a major public health concern. We report the first detection of OXA-244-producing ST131 O16:H5 Escherichia coli in three patients from two tertiary hospitals in the south-west of Germany. OXA-244 is emerging in Europe. Because of de...

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Bibliographic Details
Main Authors: Welker, Sybille (Author) , Boutin, Sébastien (Author) , Miethke, Thomas (Author) , Heeg, Klaus (Author) , Nurjadi, Dennis (Author)
Format: Article (Journal)
Language:English
Published: 19.11.2020
In: Eurosurveillance
Year: 2020, Volume: 25, Issue: 46, Pages: 1-8
ISSN:1560-7917
DOI:10.2807/1560-7917.ES.2020.25.46.2001815
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.2807/1560-7917.ES.2020.25.46.2001815
Verlag, lizenzpflichtig, Volltext: https://www.eurosurveillance.org/content/10.2807/1560-7917.ES.2020.25.46.2001815
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Author Notes:Sybille Welker, Sébastien Boutin, Thomas Miethke, Klaus Heeg, Dennis Nurjadi
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Summary:The dissemination of carbapenem-producing Gram-negative bacteria is a major public health concern. We report the first detection of OXA-244-producing ST131 O16:H5 Escherichia coli in three patients from two tertiary hospitals in the south-west of Germany. OXA-244 is emerging in Europe. Because of detection challenges, OXA-244-producing E. coli may be under-reported. The emergence of carbapenem resistance in a globally circulating high-risk clone, such as ST131 E. coli is of clinical relevance and should be monitored closely.
Item Description:Im Titel ist "OXA-244 " tiefgestellt
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Physical Description:Online Resource
ISSN:1560-7917
DOI:10.2807/1560-7917.ES.2020.25.46.2001815