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Towards a youth mental health paradigm: a perspective and roadmap

Most mental disorders have a typical onset between 12 and 25 years of age, highlighting the importance of this period for the pathogenesis, diagnosis, and treatment of mental ill-health. This perspective addresses interactions between risk and protective factors and brain development as key pillars...

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Main Authors: Uhlhaas, Peter J. (Author) , Davey, Christopher G. (Author) , Mehta, Urvakhsh Meherwan (Author) , Shah, Jai (Author) , Torous, John (Author) , Allen, Nicholas B. (Author) , Avenevoli, Shelli (Author) , Bella-Awusah, Tolulope (Author) , Chanen, Andrew (Author) , Chen, Eric Y. H. (Author) , Correll, Christoph U. (Author) , Do, Kim Q. (Author) , Fisher, Helen L. (Author) , Frangou, Sophia (Author) , Hickie, Ian B. (Author) , Keshavan, Matcheri S. (Author) , Konrad, Kerstin (Author) , Lee, Francis S. (Author) , Liu, Cindy H. (Author) , Luna, Beatriz (Author) , McGorry, Patrick D. (Author) , Meyer-Lindenberg, Andreas (Author) , Nordentoft, Merete (Author) , Öngür, Dost (Author) , Patton, George C. (Author) , Paus, Tomáš (Author) , Reininghaus, Ulrich (Author) , Sawa, Akira (Author) , Schoenbaum, Michael (Author) , Schumann, Gunter (Author) , Srihari, Vinod H. (Author) , Susser, Ezra (Author) , Verma, Swapna K. (Author) , Woo, T. Wilson (Author) , Yang, Lawrence H. (Author) , Yung, Alison R. (Author) , Wood, Stephen J. (Author)
Format: Article (Journal)
Language:English
Published: August 2023
In: Molecular psychiatry
Year: 2023, Volume: 28, Issue: 8, Pages: 3171-3181
ISSN:1476-5578
DOI:10.1038/s41380-023-02202-z
Online Access:Verlag, kostenfrei, Volltext: https://doi.org/10.1038/s41380-023-02202-z
Verlag, kostenfrei, Volltext: https://www.nature.com/articles/s41380-023-02202-z
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Author Notes:Peter J. Uhlhaas, Christopher G. Davey, Urvakhsh Meherwan Mehta, Jai Shah, John Torous, Nicholas B. Allen, Shelli Avenevoli, Tolulope Bella-Awusah, Andrew Chanen, Eric Y. H. Chen, Christoph U. Correll, Kim Q. Do, Helen L. Fisher, Sophia Frangou, Ian B. Hickie, Matcheri S. Keshavan, Kerstin Konrad, Francis S. Lee, Cindy H. Liu, Beatriz Luna, Patrick D. McGorry, Andreas Meyer-Lindenberg, Merete Nordentoft, Dost Öngür, George C. Patton, Tomáš Paus, Ulrich Reininghaus, Akira Sawa, Michael Schoenbaum, Gunter Schumann, Vinod H. Srihari, Ezra Susser, Swapna K. Verma, T. Wilson Woo, Lawrence H. Yang, Alison R. Yung and Stephen J. Wood
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Summary:Most mental disorders have a typical onset between 12 and 25 years of age, highlighting the importance of this period for the pathogenesis, diagnosis, and treatment of mental ill-health. This perspective addresses interactions between risk and protective factors and brain development as key pillars accounting for the emergence of psychopathology in youth. Moreover, we propose that novel approaches towards early diagnosis and interventions are required that reflect the evolution of emerging psychopathology, the importance of novel service models, and knowledge exchange between science and practitioners. Taken together, we propose a transformative early intervention paradigm for research and clinical care that could significantly enhance mental health in young people and initiate a shift towards the prevention of severe mental disorders.
Item Description:Online veröffentlicht: 14. August 2023
Gesehen am 10.04.2024
Physical Description:Online Resource
ISSN:1476-5578
DOI:10.1038/s41380-023-02202-z

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