The structural basis for an on-off switch controlling Gβγ-mediated inhibition of TRPM3 channels

TRPM3 channels play important roles in the detection of noxious heat and in inflammatory - thermal hyperalgesia. The activity of these ion channels i...

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Bibliographic Details
Main Authors:	Behrendt, Marc (Author) , Gruss, Fabian (Author) , Enzeroth, Raissa (Author) , Dembla, Sandeep (Author) , Zhao, Siyuan (Author) , Crassous, Pierre-Antoine (Author) , Mohr, Florian (Author) , Nys, Mieke (Author) , Louros, Nikolaos (Author) , Gallardo, Rodrigo (Author) , Zorzini, Valentina (Author) , Wagner, Doris (Author) , Economou, Anastassios (Author) , Rousseau, Frederic (Author) , Schymkowitz, Joost (Author) , Philipp, Stephan E. (Author) , Rohacs, Tibor (Author) , Ulens, Chris (Author) , Oberwinkler, Johannes (Author)
Format:	Article (Journal)
Language:	English
Published:	October 29, 2020
In:	Proceedings of the National Academy of Sciences of the United States of America Year: 2020, Volume: 117, Issue: 46, Pages: 29090-29100
ISSN:	1091-6490
DOI:	10.1073/pnas.2001177117
Online Access:	Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1073/pnas.2001177117 Verlag, lizenzpflichtig, Volltext: https://www.pnas.org/doi/abs/10.1073/pnas.2001177117
Author Notes:	Marc Behrendt, Fabian Gruss, Raissa Enzeroth, Sandeep Dembla, Siyuan Zhao, Pierre-Antoine Crassous, Florian Mohr, Mieke Nys, Nikolaos Louros, Rodrigo Gallardo, Valentina Zorzini, Doris Wagner, Anastassios Economou (ΑναστάσιoςΟικoνόμoυ), Frederic Rousseau, Joost Schymkowitz, Stephan E. Philipp, Tibor Rohacs, Chris Ulens, and Johannes Oberwinkler

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Summary:	TRPM3 channels play important roles in the detection of noxious heat and in inflammatory - thermal hyperalgesia. The activity of these ion channels i...
Item Description:	Gesehen am 17.04.2024
Physical Description:	Online Resource
ISSN:	1091-6490
DOI:	10.1073/pnas.2001177117