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Quality of life improves following laparoscopic hemifundoplication in neurologically non-impaired children with gastroesophageal reflux disease: a propensity score-matched analysis

Quality of life (QOL) data following pediatric fundoplication for gastroesophageal reflux disease (GERD) are rare. Present study assessed the QOL in neurologically non-impaired children before and after laparoscopic hemifundoplication (LHF) in comparison to healthy controls. PedsQL™ questionnaires a...

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Main Authors: Frongia, Giovanni (Author) , Weitz, Daniel (Author) , Bauer, Jan (Author) , Probst, Pascal (Author) , Steffens, Franziska (Author) , Pfisterer, Dennis (Author) , Mehrabi, Arianeb (Author) , Günther, Patrick (Author)
Format: Article (Journal)
Language:English
Published: 2022
In: Journal of investigative surgery
Year: 2022, Volume: 35, Issue: 2, Pages: 278-283
ISSN:1521-0553
DOI:10.1080/08941939.2020.1850943
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1080/08941939.2020.1850943
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Author Notes:Giovanni Frongia, Daniel Weitz, Jan Bauer, Pascal Probst, Franziska Steffens, Dennis Pfisterer, Arianeb Mehrabi, Patrick Günther
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Summary:Quality of life (QOL) data following pediatric fundoplication for gastroesophageal reflux disease (GERD) are rare. Present study assessed the QOL in neurologically non-impaired children before and after laparoscopic hemifundoplication (LHF) in comparison to healthy controls. PedsQL™ questionnaires assessed data on gastrointestinal symptoms (GIS) and general well-being (GWB) were compared in a propensity score-matched analysis (60 patients’ pairs for time-point of surgery and 51 for follow-up). Preoperatively, the LHF group had more GIS (72.2 ± 53.9 vs. 38.8 ± 31.6; p < 0.001) and a lower GWB (16.7 ± 5.5 vs. 23.8 ± 3.5, p < 0.001) compared with controls. Postoperatively, GIS decreased significantly (74.3 ± 52.9 vs. 36.3 ± 33.5; p < 0.001) and the GWB was significantly higher (16.2 ± 6.0 vs. 20.8 ± 5.8; p < 0.001). GIS were similar in the LHF and control groups (39.1 ± 36.4 vs. 40.1 ± 31.0; p = 0.885) but GWB was lower in the LHF group than the control group (20.5 ± 6.3 vs. 23.4 ± 3.9; p = 0.009). QOL significantly improves after LHF in neurologically non-impaired children.
Item Description:Online veröffentlicht: 29. November 2020
Gesehen am 17.04.2024
Physical Description:Online Resource
ISSN:1521-0553
DOI:10.1080/08941939.2020.1850943

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