Quality of life improves following laparoscopic hemifundoplication in neurologically non-impaired children with gastroesophageal reflux disease: a propensity score-matched analysis
Quality of life (QOL) data following pediatric fundoplication for gastroesophageal reflux disease (GERD) are rare. Present study assessed the QOL in neurologically non-impaired children before and after laparoscopic hemifundoplication (LHF) in comparison to healthy controls. PedsQL™ questionnaires a...
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| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article (Journal) |
| Language: | English |
| Published: |
2022
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| In: |
Journal of investigative surgery
Year: 2022, Volume: 35, Issue: 2, Pages: 278-283 |
| ISSN: | 1521-0553 |
| DOI: | 10.1080/08941939.2020.1850943 |
| Online Access: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1080/08941939.2020.1850943 |
| Author Notes: | Giovanni Frongia, Daniel Weitz, Jan Bauer, Pascal Probst, Franziska Steffens, Dennis Pfisterer, Arianeb Mehrabi, Patrick Günther |
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| 520 | |a Quality of life (QOL) data following pediatric fundoplication for gastroesophageal reflux disease (GERD) are rare. Present study assessed the QOL in neurologically non-impaired children before and after laparoscopic hemifundoplication (LHF) in comparison to healthy controls. PedsQL™ questionnaires assessed data on gastrointestinal symptoms (GIS) and general well-being (GWB) were compared in a propensity score-matched analysis (60 patients’ pairs for time-point of surgery and 51 for follow-up). Preoperatively, the LHF group had more GIS (72.2 ± 53.9 vs. 38.8 ± 31.6; p < 0.001) and a lower GWB (16.7 ± 5.5 vs. 23.8 ± 3.5, p < 0.001) compared with controls. Postoperatively, GIS decreased significantly (74.3 ± 52.9 vs. 36.3 ± 33.5; p < 0.001) and the GWB was significantly higher (16.2 ± 6.0 vs. 20.8 ± 5.8; p < 0.001). GIS were similar in the LHF and control groups (39.1 ± 36.4 vs. 40.1 ± 31.0; p = 0.885) but GWB was lower in the LHF group than the control group (20.5 ± 6.3 vs. 23.4 ± 3.9; p = 0.009). QOL significantly improves after LHF in neurologically non-impaired children. | ||
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