Role of sparing of puboprostatic ligaments on continence recovery after radical prostatectomy: a randomized controlled trial

Abstract Objective Sparing of puboprostatic ligaments (PPLs) during radical prostatectomy was introduced as a technique to improve urinary continence. This study aims to study the effect of sparing of PPLs during laparoscopic radical prostatectomy in terms of continence during the first 3 months. Me...

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Main Authors: Assem, Akram (Author) , Youssif, Tamer Abou (Author) , Hamdy, Seif M. (Author) , Beltagy, Ahmad M. (Author) , Gözen, Ali Serdar (Author)
Format: Article (Journal)
Language:English
Published: 2021-01-02
In: Scandinavian journal of urology
Year: 2021, Volume: 55, Issue: 1, Pages: 22-26
ISSN:2168-1813
DOI:10.1080/21681805.2020.1849389
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1080/21681805.2020.1849389
Verlag, lizenzpflichtig, Volltext: https://medicaljournalssweden.se/SJU/article/view/11767
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Author Notes:Akram Assem, Tamer Abou Youssif, Seif M. Hamdy, Ahmad M. Beltagy, Ali Serdar Gozen
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Summary:Abstract Objective Sparing of puboprostatic ligaments (PPLs) during radical prostatectomy was introduced as a technique to improve urinary continence. This study aims to study the effect of sparing of PPLs during laparoscopic radical prostatectomy in terms of continence during the first 3 months. Methods A total of 74 patients, diagnosed with clinically localized prostate cancer, were randomly assigned to two equal groups; PPLs division and sparing during LRP. Based on the number of daily used pads, both groups completed 3 months follow-up to assess continence recovery. The effects of age, preoperative total prostate-specific antigen (PSA) and clinical tumor stage on continence recovery were also studied. The study was registered and approved by the Ethics Committee of Alexandria University-Faculty of Medicine (Protocol No. 0201074). Results Seventy-four patients were enrolled, with a mean age of 63.8 years. Baseline characteristics were comparable, except significantly higher mean PSA in the division group. Sixty patients were continent (0-1 pad/day) at 3 months follow-up. Continence was significantly better in the sparing than division group at 1 week after catheter removal (67.6% vs 40.5%, p = 0.01), at 1 month (73% vs 45.9%, p = 0.009) and 2 months (89.2% vs 51.4%, p = 0.0001). At 3 months follow-up, there was no significant difference between both groups (83.3% vs 78.4% for sparing and division groups, respectively; p = 0.28). Moreover, continence was significantly improved at 3 months compared to 1 week in both groups. Conclusion Sparing of puboprostatic ligaments during radical prostatectomy significantly improves postoperative early recovery of urinary continence.
Item Description:Gesehen am 17.04.2024
Physical Description:Online Resource
ISSN:2168-1813
DOI:10.1080/21681805.2020.1849389