Adherence to the EAT-Lancet reference diet is associated with a reduced risk of incident cancer and all-cause mortality in UK adults

Food systems have been identified as significant contributors to the global environmental emergency. However, there is no universally agreed-upon definition of what constitutes a planetary healthy, sustainable diet. In our study, we investigated the association between the EAT-Lancet reference diet,...

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Main Authors: Karavasiloglou, Nena (Author) , Thompson, Alysha S. (Author) , Pestoni, Giulia (Author) , Knuppel, Anika (Author) , Papier, Keren (Author) , Cassidy, Aedín (Author) , Kühn, Tilman (Author) , Rohrmann, Sabine (Author)
Format: Article (Journal)
Language:English
Published: 15 December 2023
In: One earth
Year: 2023, Volume: 6, Issue: 12, Pages: 1726-1734
ISSN:2590-3322
DOI:10.1016/j.oneear.2023.11.002
Online Access:Verlag, kostenfrei, Volltext: https://doi.org/10.1016/j.oneear.2023.11.002
Verlag, kostenfrei, Volltext: https://www.sciencedirect.com/science/article/pii/S2590332223005055
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Author Notes:Nena Karavasiloglou, Alysha S. Thompson, Giulia Pestoni, Anika Knuppel, Keren Papier, Aedín Cassidy, Tilman Kühn, and Sabine Rohrmann

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520 |a Food systems have been identified as significant contributors to the global environmental emergency. However, there is no universally agreed-upon definition of what constitutes a planetary healthy, sustainable diet. In our study, we investigated the association between the EAT-Lancet reference diet, a diet within the planetary boundaries, and incident cancer, incident major cardiovascular events, and all-cause mortality. Higher adherence to the EAT-Lancet reference diet was associated with lower incident cancer risk (hazard ratio [HR]continuous: 0.99; 95% confidence interval [CI]: 0.98-0.99]) and lower all-cause mortality (HR continuous: 0.98; 95% CI: 0.98-0.99), while mostly null associations were detected for major cardiovascular event risk (HR continuous: 1.00; 95% CI: 0.98-1.01). Stratified analyses using potentially modifiable risk factors led to similar results. Our findings, in conjunction with the existing literature, support that adoption of the EAT-Lancet reference diet could have a benefit for the prevention of non-communicable diseases. 
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