Assessing long-term, vestibulotoxic side effects after gentamicin therapy in neonatal sepsis or infection using video head impulse test
Question: Does gentamicin therapy in children with neonatal sepsis or infection lead to persistent vestibulotoxicity? Findings: In a single-center, prospective cross-sectional study video head impulse test (VHIT) was performed to evaluate vestibular function in 23 children aged 3-7 years at least th...
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| Hauptverfasser: | , , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
26 February 2024
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| In: |
Frontiers in Pediatrics
Year: 2024, Jahrgang: 12, Pages: 1-17 |
| ISSN: | 2296-2360 |
| DOI: | 10.3389/fped.2024.1366074 |
| Online-Zugang: | Verlag, kostenfrei, Volltext: https://doi.org/10.3389/fped.2024.1366074 Verlag, kostenfrei, Volltext: https://www.frontiersin.org/articles/10.3389/fped.2024.1366074 
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| Verfasserangaben: | Lena Zaubitzer, Anja Kotzur, Stefan Hegemann, Nicole Rotter and Angela Schell |
| Zusammenfassung: | Question: Does gentamicin therapy in children with neonatal sepsis or infection lead to persistent vestibulotoxicity? Findings: In a single-center, prospective cross-sectional study video head impulse test (VHIT) was performed to evaluate vestibular function in 23 children aged 3-7 years at least three years after intravenous gentamicin therapy for neonatal sepsis or infection.Although eleven children showed abnormal results in vestibular testing, they did not present with a clinically significant vestibular hypofunction or delayed motoric development.VHIT can serve as a sensitive investigation method for the screening of posttherapeutic vestibulotoxic side effects after gentamicin therapy in children. |
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| Beschreibung: | Gesehen am 28.05.2024 |
| Beschreibung: | Online Resource |
| ISSN: | 2296-2360 |
| DOI: | 10.3389/fped.2024.1366074 |