Effects of Ionizing radiation on Cardiac Implantable Electronic Devices (CIEDs) in patients with esophageal cancer undergoing radiotherapy: a pilot study
(1) Background: The prevalence of cancer patients relying on cardiac implantable electronic device (CIED) is steadily rising. The aim of this study was to evaluate RT-related malfunctions of CIEDs. (2) Methods: We retrospectively analyze sixteen patients with esophageal cancer who were treated with...
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| Main Authors: | , , , , , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
28 January 2024
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| In: |
Cancers
Year: 2024, Volume: 16, Issue: 3, Pages: 1-11 |
| ISSN: | 2072-6694 |
| DOI: | 10.3390/cancers16030555 |
| Online Access: | Verlag, kostenfrei, Volltext: https://doi.org/10.3390/cancers16030555 Verlag, kostenfrei, Volltext: https://www.mdpi.com/2072-6694/16/3/555 
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| Author Notes: | Davut D. Uzun, Janek Salatzki, Panagiotis Xynogalos, Norbert Frey, Juergen Debus and Kristin Lang |
| Summary: | (1) Background: The prevalence of cancer patients relying on cardiac implantable electronic device (CIED) is steadily rising. The aim of this study was to evaluate RT-related malfunctions of CIEDs. (2) Methods: We retrospectively analyze sixteen patients with esophageal cancer who were treated with radiotherapy between 2012 and 2022 at the University Hospital Heidelberg. All patients underwent systemic evaluation including pre-therapeutic cardiological examinations of the CIED functionality and after every single irradiation. (3) Results: Sixteen patients, predominantly male (14) with a mean age of 77 (range: 56-85) years were enrolled. All patients received 28 fractions of radiotherapy with a cumulative total dose 58.8 Gy. The mean maximum dose at the CIEDs was 1.8 Gy. Following radiotherapy and during the one-year post-radiation follow-up period, there were no registered events associated with the treatment in this evaluation. (4) Conclusion: The study did not observe any severe CIED malfunctions following each radiation fraction or after completion of RT. Strict selection of photon energy and alignment with manufacturer-recommended dose limits appear to be important. Our study showed no major differences in the measured values of the pacing threshold, sensing threshold and lead impedance after RT. |
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| Item Description: | Gesehen am 12.06.2024 |
| Physical Description: | Online Resource |
| ISSN: | 2072-6694 |
| DOI: | 10.3390/cancers16030555 |