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Thrombolysis for ischaemic stroke despite direct oral anticoagulation

Intravenous thrombolysis is not recommended in anticoagulated patients receiving direct oral anticoagulants (DOACs) and a recent intake within the last 48 hours in US and European guidelines. However, three observational studies now suggest safety of thrombolysis in patients with recent intake of DO...

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Bibliographic Details
Main Authors: Purrucker, Jan (Author) , Meinel, Thomas R. (Author) , Wilson, Duncan (Author) , Xian, Ying (Author) , Wu, Teddy Y. (Author) , Seiffge, David (Author)
Format: Article (Journal)
Language:English
Published: January 31, 2024
In: Stroke and vascular neurology
Year: 2024, Pages: 1-3
ISSN:2059-8696
DOI:10.1136/svn-2023-002727
Online Access:Verlag, kostenfrei, Volltext: https://doi.org/10.1136/svn-2023-002727
Verlag, kostenfrei, Volltext: https://svn.bmj.com/content/early/2024/01/30/svn-2023-002727
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Author Notes:Jan C. Purrucker, Thomas R. Meinel, Duncan Wilson, Ying Xian, Teddy Y. Wu, David J. Seiffge
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Summary:Intravenous thrombolysis is not recommended in anticoagulated patients receiving direct oral anticoagulants (DOACs) and a recent intake within the last 48 hours in US and European guidelines. However, three observational studies now suggest safety of thrombolysis in patients with recent intake of DOACs, and thus support previous experimental data. In this perspective, the current evidence and practical consequences are discussed.
Item Description:Gesehen am 17.06.2024
Physical Description:Online Resource
ISSN:2059-8696
DOI:10.1136/svn-2023-002727

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