Phenotypes and treatment outcomes in idiopathic pulmonary arterial hypertension patients with comorbidities
Idiopathic pulmonary arterial hypertension (IPAH) is often diagnosed in elderly patients with many comorbidities. Whereas a clear treatment strategy and risk assessment is recommended for patients with rare classical IPAH, monotherapy with phosphodiesterase type 5 inhibitors or endothelin receptor a...
Saved in:
| Main Authors: | , , , , , , , , |
|---|---|
| Format: | Article (Journal) |
| Language: | English |
| Published: |
January 29, 2024
|
| In: |
ERJ Open Research
Year: 2024, Volume: 10, Issue: 1, Pages: 1-18 |
| ISSN: | 2312-0541 |
| DOI: | 10.1183/23120541.00668-2023 |
| Online Access: | Verlag, kostenfrei, Volltext: https://doi.org/10.1183/23120541.00668-2023 Verlag, kostenfrei, Volltext: https://openres.ersjournals.com/content/10/1/00668-2023 
|
| Author Notes: | Dirk Skowasch, Hans Klose, Ralf Ewert, Heinrike Wilkens, Manuel Richter, Stephan Rosenkranz, Gesine Setzer, Ekkehard Grünig and Michael Halank |
| Summary: | Idiopathic pulmonary arterial hypertension (IPAH) is often diagnosed in elderly patients with many comorbidities. Whereas a clear treatment strategy and risk assessment is recommended for patients with rare classical IPAH, monotherapy with phosphodiesterase type 5 inhibitors or endothelin receptor antagonists followed by regular follow-up and individualised therapy should be used for patients with many cardiopulmonary comorbidities. Here, we focus on these patients with IPAH and comorbidities, present a review of the literature with a focus on recently published work and summarise factors that may help to provide guidance for individualised treatment approaches in such patients. |
|---|---|
| Item Description: | Gesehen am 25.06.2024 |
| Physical Description: | Online Resource |
| ISSN: | 2312-0541 |
| DOI: | 10.1183/23120541.00668-2023 |