Buchumschlag

Phenotypes and treatment outcomes in idiopathic pulmonary arterial hypertension patients with comorbidities

Idiopathic pulmonary arterial hypertension (IPAH) is often diagnosed in elderly patients with many comorbidities. Whereas a clear treatment strategy and risk assessment is recommended for patients with rare classical IPAH, monotherapy with phosphodiesterase type 5 inhibitors or endothelin receptor a...

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Hauptverfasser: Skowasch, Dirk (Verfasst von) , Klose, Hans (Verfasst von) , Ewert, Ralf (Verfasst von) , Wilkens, Heinrike (Verfasst von) , Richter, Manuel (Verfasst von) , Rosenkranz, Stephan (Verfasst von) , Setzer, Gesine (Verfasst von) , Grünig, Ekkehard (Verfasst von) , Halank, Michael (Verfasst von)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: January 29, 2024
In: ERJ Open Research
Year: 2024, Jahrgang: 10, Heft: 1, Pages: 1-18
ISSN:2312-0541
DOI:10.1183/23120541.00668-2023
Online-Zugang:Verlag, kostenfrei, Volltext: https://doi.org/10.1183/23120541.00668-2023
Verlag, kostenfrei, Volltext: https://openres.ersjournals.com/content/10/1/00668-2023
Volltext
Verfasserangaben:Dirk Skowasch, Hans Klose, Ralf Ewert, Heinrike Wilkens, Manuel Richter, Stephan Rosenkranz, Gesine Setzer, Ekkehard Grünig and Michael Halank
Beschreibung
Zusammenfassung:Idiopathic pulmonary arterial hypertension (IPAH) is often diagnosed in elderly patients with many comorbidities. Whereas a clear treatment strategy and risk assessment is recommended for patients with rare classical IPAH, monotherapy with phosphodiesterase type 5 inhibitors or endothelin receptor antagonists followed by regular follow-up and individualised therapy should be used for patients with many cardiopulmonary comorbidities. Here, we focus on these patients with IPAH and comorbidities, present a review of the literature with a focus on recently published work and summarise factors that may help to provide guidance for individualised treatment approaches in such patients.
Beschreibung:Gesehen am 25.06.2024
Beschreibung:Online Resource
ISSN:2312-0541
DOI:10.1183/23120541.00668-2023

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