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Identifying symptoms of ADHD and disruptive behavior disorders most strongly associated with functional impairment in children: a symptom-level approach

To enhance the understanding of how symptoms of attention-deficit/hyperactivity disorder (ADHD) and disruptive behavior disorders such as oppositional defiant disorder (ODD), conduct disorder (CD), including callous-unemotional (CU) traits, differentially relate to functional impairment (FI). Partic...

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Main Authors: Thöne, Ann-Kathrin (Author) , Dose, Christina (Author) , Junghänel, Michaela (Author) , Hautmann, Christopher (Author) , Jendreizik, Lea Teresa (Author) , Treier, Anne-Katrin (Author) , Vetter, Paula (Author) , Wirth, Elena von (Author) , Banaschewski, Tobias (Author) , Becker, Katja (Author) , Brandeis, Daniel (Author) , Dürrwächter, Ute (Author) , Geissler, Julia (Author) , Hebebrand, Johannes (Author) , Hohmann, Sarah (Author) , Holtmann, Martin (Author) , Huss, Michael (Author) , Jans, Thomas (Author) , Kaiser, Anna (Author) , Ketter, Johanna (Author) , Legenbauer, Tanja (Author) , Millenet, Sabina (Author) , Poustka, Luise (Author) , Renner, Tobias (Author) , Romanos, Marcel (Author) , Sandersleben, Henrik Uebel-von (Author) , Schneider, Priska S. (Author) , Wenning, Jasmin (Author) , Ziegler, Mirjam (Author) , Görtz-Dorten, Anja (Author) , Döpfner, Manfred (Author)
Format: Article (Journal)
Language:English
Published: June 2023
In: Journal of psychopathology and behavioral assessment
Year: 2023, Volume: 45, Issue: 2, Pages: 277-293
ISSN:1573-3505
DOI:10.1007/s10862-023-10025-z
Online Access:Verlag, kostenfrei, Volltext: https://doi.org/10.1007/s10862-023-10025-z
Verlag, kostenfrei, Volltext: https://link.springer.com/article/10.1007/s10862-023-10025-z
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Author Notes:Ann-Kathrin Thöne, Christina Dose, Michaela Junghänel, Christopher Hautmann, Lea Teresa Jendreizik, Anne-Katrin Treier, Paula Vetter, Elena von Wirth, Tobias Banaschewski, Katja Becker, Daniel Brandeis, Ute Dürrwächter, Julia Geissler, Johannes Hebebrand, Sarah Hohmann, Martin Holtmann, Michael Huss, Thomas Jans, Anna Kaiser, Johanna Ketter, Tanja Legenbauer, Sabina Millenet, Luise Poustka, Tobias Renner, Marcel Romanos, Henrik Uebel-von Sandersleben, Priska S. Schneider, Jasmin Wenning, Mirjam Ziegler, Anja Görtz-Dorten, Manfred Döpfner
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Summary:To enhance the understanding of how symptoms of attention-deficit/hyperactivity disorder (ADHD) and disruptive behavior disorders such as oppositional defiant disorder (ODD), conduct disorder (CD), including callous-unemotional (CU) traits, differentially relate to functional impairment (FI). Participants were 474 German school-age children (age: M = 8.90, SD = 1.49, 81% male) registered for participation in the ESCAschool trial (ESCAschool: Evidence-based, Stepped Care of ADHD in school-aged children). Clinicians assessed the severity of individual symptoms and five FI domains specifically associated with ADHD symptoms or ODD/CD/CU symptoms using a semi-structured clinical interview. We conducted two multiple linear regression analyses, combined with relative importance analyses, to determine the impact of individual symptoms on global FI associated with ADHD and ODD/CD/CU symptoms. Next, we estimated two networks and identified the strongest associations of ADHD symptoms or ODD/CD/CU symptoms with the five FI domains. Symptoms varied substantially in their associations with global FI. The ADHD symptom Easily Distracted (15%) and ODD symptom Argues with Adults (10%) contributed most strongly to the total explained variance. FI related to academic performance, home life and family members, and psychological strain were most strongly associated with ADHD inattention symptoms, whereas FI related to relationships with adults and relationships with children and recreational activities were most strongly associated with hyperactivity-impulsivity symptoms. By comparison, the ODD/CD/CU symptoms most closely linked to FI domains originated from the ODD and CD dimensions. Our findings contribute to a growing body of literature on the importance of analyzing individual symptoms and highlight that symptom-based approaches can be clinically useful.
Item Description:Online veröffentlicht: 3. März 2023
Gesehen am 07.08.2024
Physical Description:Online Resource
ISSN:1573-3505
DOI:10.1007/s10862-023-10025-z

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