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Gray matter covariations and core symptoms of autism: the EU-AIMS Longitudinal European Autism Project

Voxel-based morphometry (VBM) studies in autism spectrum disorder (autism) have yielded diverging results. This might partly be attributed to structural alterations being associating with the combined influence of several regions rather than with a single region. Further, these structural covariatio...

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Main Authors: Mei, Ting (Author) , Llera, Alberto (Author) , Floris, Dorothea L. (Author) , Forde, Natalie J. (Author) , Tillmann, Julian (Author) , Durston, Sarah (Author) , Mößnang, Carolin Ulrike (Author) , Banaschewski, Tobias (Author) , Holt, Rosemary J. (Author) , Baron-Cohen, Simon (Author) , Rausch, Annika (Author) , Loth, Eva (Author) , Dell’Acqua, Flavio (Author) , Charman, Tony (Author) , Murphy, Declan G. M. (Author) , Ecker, Christine (Author) , Beckmann, Christian F. (Author) , Buitelaar, Jan K. (Author)
Format: Article (Journal)
Language:English
Published: 2020
In: Molecular autism
Year: 2020, Volume: 11, Issue: 1, Pages: 86
ISSN:2040-2392
DOI:10.1186/s13229-020-00389-4
Online Access:Verlag, kostenfrei, Volltext: https://doi.org/10.1186/s13229-020-00389-4
Verlag, kostenfrei, Volltext: https://molecularautism.biomedcentral.com/articles/10.1186/s13229-020-00389-4
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Author Notes:Ting Mei, Alberto Llera, Dorothea L. Floris, Natalie J. Forde, Julian Tillmann, Sarah Durston, Carolin Moessnang, Tobias Banaschewski, Rosemary J. Holt, Simon Baron-Cohen, Annika Rausch, Eva Loth, Flavio Dell’Acqua, Tony Charman, Declan G. M. Murphy, Christine Ecker, Christian F. Beckmann and Jan K. Buitelaar on behalf of the EU-AIMS LEAP group
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Summary:Voxel-based morphometry (VBM) studies in autism spectrum disorder (autism) have yielded diverging results. This might partly be attributed to structural alterations being associating with the combined influence of several regions rather than with a single region. Further, these structural covariation differences may relate to continuous measures of autism rather than with categorical case-control contrasts. The current study aimed to identify structural covariation alterations in autism, and assessed canonical correlations between brain covariation patterns and core autism symptoms.
Item Description:Gesehen am 08.08.2024
Physical Description:Online Resource
ISSN:2040-2392
DOI:10.1186/s13229-020-00389-4

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