Identification and management of Lynch syndrome in the Middle East and North African countries: outcome of a survey in 12 countries
Lynch syndrome (LS), the most common inherited form of colorectal cancer (CRC), is responsible for 3% of all cases of CRC. LS is caused by a mismatch repair gene defect and is characterized by a high risk for CRC, endometrial cancer and several other cancers. Identification of LS is of utmost import...
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| Hauptverfasser: | , , , , , , , , , , , , , , , , , , , , , , , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
2021
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| In: |
Familial cancer
Year: 2021, Jahrgang: 20, Heft: 3, Pages: 215-221 |
| ISSN: | 1573-7292 |
| DOI: | 10.1007/s10689-020-00211-3 |
| Online-Zugang: | Verlag, kostenfrei, Volltext: https://doi.org/10.1007/s10689-020-00211-3 Verlag, kostenfrei, Volltext: https://link.springer.com/article/10.1007/s10689-020-00211-3 |
| Verfasserangaben: | Mohammad Sina, Zeinab Ghorbanoghli, Amal Abedrabbo, Fahd Al-Mulla, Rihab Ben Sghaier, Marie-Pierre Buisine, George Cortas, Ladan Goshayeshi, Andreas Hadjisavvas, Wail Hammoudeh, Waseem Hamoudi, Carol Jabari, Maria A. Loizidou, Keivan Majidzadeh-A, Makia J. Marafie, Gurbankhan Muslumov, Laila Rifai, Rania Abu Seir, Suzan M. Talaat, Berrin Tunca, Hadia Ziada-Bouchaar, Mary E. Velthuizen, Ala I. Sharara, Aysel Ahadova, Demetra Georgiou, Hans F. A. Vasen, on behalf of the Middle East Network on Hereditary Colorectal Cancer (HCCN-ME) |
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| 520 | |a Lynch syndrome (LS), the most common inherited form of colorectal cancer (CRC), is responsible for 3% of all cases of CRC. LS is caused by a mismatch repair gene defect and is characterized by a high risk for CRC, endometrial cancer and several other cancers. Identification of LS is of utmost importance because colonoscopic surveillance substantially improves a patient’s prognosis. Recently, a network of physicians in Middle Eastern and North African (ME/NA) countries was established to improve the identification and management of LS families. The aim of the present survey was to evaluate current healthcare for families with LS in this region. | ||
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