Regulation of apoptosis in the immune system
Apoptosis in T and B lymphocytes is involved in all fundamental processes in the immune system. It is a mechanism to regulate the course of an immune response and to establish immunological memory as well as central and peripheral tolerance. Apoptosis in lymphocytes is regulated by gene products tha...
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| Main Authors: | , , , , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
1994
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| In: |
Current opinion in immunology
Year: 1994, Volume: 6, Issue: 2, Pages: 279-289 |
| ISSN: | 1879-0372 |
| DOI: | 10.1016/0952-7915(94)90102-3 |
| Online Access: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1016/0952-7915(94)90102-3 Verlag, lizenzpflichtig, Volltext: https://www.sciencedirect.com/science/article/pii/0952791594901023 
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| Author Notes: | Peter H. Krammer, Iris Behrmann, Peter Daniel, Jens Dhein, Klaus-Michael Debatin |
| Summary: | Apoptosis in T and B lymphocytes is involved in all fundamental processes in the immune system. It is a mechanism to regulate the course of an immune response and to establish immunological memory as well as central and peripheral tolerance. Apoptosis in lymphocytes is regulated by gene products that induce or block this process. Elucidating the molecular basis for sensitivity and resistance towards induction of apoptosis is the key to the understanding of the development of the immune system, basic immune reactions and the pathogenesis of autoimmune diseases, AIDS and cancer. |
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| Item Description: | Elektronische Reproduktion der Druck-Ausgabe 12. September 2003 Gesehen am 19.09.2024 |
| Physical Description: | Online Resource |
| ISSN: | 1879-0372 |
| DOI: | 10.1016/0952-7915(94)90102-3 |