Sex-specific cardiovascular remodeling leads to a divergent sex-dependent development of heart failure in aged hypertensive rats
The prevalence of heart failure with preserved ejection fraction (HFpEF) is continuously rising and predominantly affects older women often hypertensive and/or obese or diabetic. Indeed, there is evidence on sex differences in the development of HF. Hence, we studied cardiovascular performance depen...
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| Main Authors: | , , , , , , , , , , , , , , , , , , , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
2024
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| In: |
GeroScience
Year: 2024, Volume: 46, Issue: 5, Pages: 4543-4561 |
| ISSN: | 2509-2723 |
| DOI: | 10.1007/s11357-024-01160-w |
| Online Access: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1007/s11357-024-01160-w |
| Author Notes: | Árpád Kovács, Saltanat Zhazykbayeva, Melissa Herwig, Gábor Á. Fülöp, Tamás Csípő, Nikolett Oláh, Roua Hassoun, Heidi Budde, Hersh Osman, Mustafa Kaçmaz, Kornelia Jaquet, Dániel Priksz, Béla Juhász, Ibrahim Akin, Zoltán Papp, Wolfgang E. Schmidt, Andreas Mügge, Ibrahim El-Battrawy, Attila Tóth, Nazha Hamdani |
| Summary: | The prevalence of heart failure with preserved ejection fraction (HFpEF) is continuously rising and predominantly affects older women often hypertensive and/or obese or diabetic. Indeed, there is evidence on sex differences in the development of HF. Hence, we studied cardiovascular performance dependent on sex and age as well as pathomechanisms on a cellular and molecular level. |
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| Item Description: | Online veröffentlicht: 24. April 2024 Gesehen am 27.09.2024 |
| Physical Description: | Online Resource |
| ISSN: | 2509-2723 |
| DOI: | 10.1007/s11357-024-01160-w |