Accelerated high sensitivity troponin diagnostics: ready for an even faster pace?

This editorial refers to "Point-of-care high-sensitivity cardiac troponin in suspected acute myocardial infarction assessed at baseline and 2 h" by L. Cullen et al., https://doi.org/10.1093/eurheartj/ehae343.High sensitivity cardiac troponin (hs-cTn) assays were introduced into clinical ro...

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Hauptverfasser: Giannitsis, Evangelos (VerfasserIn) , Frey, Norbert (VerfasserIn) , Katus, Hugo (VerfasserIn)
Dokumenttyp: Article (Journal) Editorial
Sprache:Englisch
Veröffentlicht: 11 June 2024
In: European heart journal
Year: 2024, Jahrgang: 45, Heft: 28, Pages: 2516-2518
ISSN:1522-9645
DOI:10.1093/eurheartj/ehae344
Online-Zugang:Verlag, kostenfrei, Volltext: https://doi.org/10.1093/eurheartj/ehae344
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Verfasserangaben:Evangelos Giannitsis, Norbert Frey, and Hugo A. Katus
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Zusammenfassung:This editorial refers to "Point-of-care high-sensitivity cardiac troponin in suspected acute myocardial infarction assessed at baseline and 2 h" by L. Cullen et al., https://doi.org/10.1093/eurheartj/ehae343.High sensitivity cardiac troponin (hs-cTn) assays were introduced into clinical routine almost 15 years ago.1 These more sensitive assays allowed the detection of even minute changes of cTn in chest pain patients, resulting in an earlier diagnosis of myocardial infarction (MI) than that achieved by conventional cTn assay formats. Well-controlled studies using hs-cTn assays then indicated that minor elevations of cTn or even detectable cTn levels in the upper normal range carry important information on cardiovascular risk and may aid in the triage of emergency room patients with or without acute coronary syndrome (ACS). In order to ‘decongest’ crowded emergency units and to expedite management, accelerated diagnostic protocols using high sensitivity assays have been carefully evaluated by many research groups. As a result, the 2023 ESC ACS Guidelines2 state that hs-cTn assays should be used in an ESC 0/1-, ESC 0/2-, or 0/3-h algorithm.
Beschreibung:Gesehen am 14.10.2024
Beschreibung:Online Resource
ISSN:1522-9645
DOI:10.1093/eurheartj/ehae344