Comparative study of the antiproliferative activity of heterometallic carbene gold(I)-platinum(II) and gold(I)-palladium(II) complexes in cancer cell lines

The stepwise, one-pot synthesis of heterobimetallic carbene gold(I) platinum(II) complexes from readily available starting materials is presented. The protecting group free methodology is based on the graduated nucleophilicities of aliphatic and aromatic amines as linkers between both metal centers....

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Main Authors:	Dietl, Martin C. (Author) , Maag, Melina (Author) , Ber, Sophia (Author) , Rominger, Frank (Author) , Rudolph, Matthias (Author) , Caligiuri, Isabella (Author) , Andele, Pacome K. (Author) , Mkhalid, Ibraheem A. I. (Author) , Rizzolio, Flavio (Author) , Nogara, Pablo A. (Author) , Orian, Laura (Author) , Scattolin, Thomas (Author) , Hashmi, A. Stephen K. (Author)
Format:	Article (Journal)
Language:	English
Published:	29 Aug 2024
In:	Chemical science Year: 2024, Volume: 15, Issue: 37, Pages: 15291-15298
ISSN:	2041-6539
DOI:	10.1039/D4SC04585H
Online Access:	Verlag, kostenfrei, Volltext: https://doi.org/10.1039/D4SC04585H Verlag, kostenfrei, Volltext: https://pubs.rsc.org/en/content/articlelanding/2024/sc/d4sc04585h
Author Notes:	Martin C. Dietl, Melina Maag, Sophia Ber, Frank Rominger, Matthias Rudolph, Isabella Caligiuri, Pacome K. Andele, Ibraheem A.I. Mkhalid, Flavio Rizzolio, Pablo A. Nogara, Laura Orian, Thomas Scattolin and A. Stephen K. Hashmi