Sarcoma ecotypes determine immunotherapy benefit
Sarcomas are heterogeneous connective tissue tumors that occur at various anatomic sites and are generally difficult to treat. Cell states in sarcoma ecosystems are now shown to be conserved across multiple subtypes and associated with response to immunotherapy and patient outcome.
Saved in:
| Main Authors: | , |
|---|---|
| Format: | Article (Journal) |
| Language: | English |
| Published: |
29 April 2024
|
| In: |
Nature cancer
Year: 2024, Volume: 5, Issue: 4, Pages: 536-538 |
| ISSN: | 2662-1347 |
| DOI: | 10.1038/s43018-024-00762-9 |
| Online Access: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1038/s43018-024-00762-9 Verlag, lizenzpflichtig, Volltext: https://www.nature.com/articles/s43018-024-00762-9 
|
| Author Notes: | Johanna Wagne & Stefan Fröhling |
| Summary: | Sarcomas are heterogeneous connective tissue tumors that occur at various anatomic sites and are generally difficult to treat. Cell states in sarcoma ecosystems are now shown to be conserved across multiple subtypes and associated with response to immunotherapy and patient outcome. |
|---|---|
| Item Description: | Gesehen am 16.10.2024 |
| Physical Description: | Online Resource |
| ISSN: | 2662-1347 |
| DOI: | 10.1038/s43018-024-00762-9 |