Non‐vitamin‐K‐antagonist oral anticoagulants (NOACs) after acute myocardial infarction: a network meta‐analysis : [intervention review]

Background: Balancing the risk of bleeding and thrombosis after acute myocardial infarction (AMI) is challenging, and the optimal antithrombotic therapy remains uncertain. The potential of non-vitamin K antagonist oral anticoagulants (NOACs) to prevent ischaemic cardiovascular events is promising, b...

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Main Authors: Al Said, Samer (Author) , Kaier, Klaus (Author) , Sumaya, Wael (Author) , Alsaid, Dima (Author) , Dürschmied, Daniel (Author) , Storey, Robert F. (Author) , Gibson, C. Michael (Author) , Westermann, Dirk (Author) , Alabed, Samer (Author)
Format: Article (Journal) Chapter/Article
Language:English
Published: 24 January 2024
In: Cochrane library
Year: 2024, Issue: 1, Pages: i-iii, 1-110
ISSN:1465-1858
DOI:10.1002/14651858.CD014678.pub2
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1002/14651858.CD014678.pub2
Verlag, lizenzpflichtig, Volltext: http://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD014678.pub2/full
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Author Notes:Samer Al Said, Klaus Kaier, Wael Sumaya, Dima Alsaid, Daniel Duerschmied, Robert F Storey, C. Michael Gibson, Dirk Westermann, Samer Alabed
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Summary:Background: Balancing the risk of bleeding and thrombosis after acute myocardial infarction (AMI) is challenging, and the optimal antithrombotic therapy remains uncertain. The potential of non-vitamin K antagonist oral anticoagulants (NOACs) to prevent ischaemic cardiovascular events is promising, but the evidence remains limited. Objectives: To evaluate the efficacy and safety of non-vitamin-K-antagonist oral anticoagulants (NOACs) in addition to background antiplatelet therapy, compared with placebo, antiplatelet therapy, or both, after acute myocardial infarction (AMI) in people without an indication for anticoagulation (i.e. atrial fibrillation or venous thromboembolism).
Item Description:Gesehen am 21.10.2024
Physical Description:Online Resource
ISSN:1465-1858
DOI:10.1002/14651858.CD014678.pub2