Textural heterogeneity of liver lesions in CT imaging: comparison of colorectal and pancreatic metastases : hepatobiliary

Tumoral heterogeneity poses a challenge for personalized cancer treatments. Especially in metastasized cancer, it remains a major limitation for successful targeted therapy, often leading to drug resistance due to tumoral escape mechanisms. This work explores a non-invasive radiomics-based approach...

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Main Authors: Pietsch, Friedrich L. (Author) , Haag, Florian (Author) , Ayx, Isabelle (Author) , Grawe, Freba (Author) , Vellala, Abhinay K. (Author) , Schönberg, Stefan (Author) , Froelich, Matthias F. (Author) , Tharmaseelan, Hishan (Author)
Format: Article (Journal)
Language:English
Published: December 2024
In: Abdominal radiology
Year: 2024, Volume: 49, Issue: 12, Pages: 4295-4306
ISSN:2366-0058
DOI:10.1007/s00261-024-04511-5
Online Access:Verlag, kostenfrei, Volltext: https://doi.org/10.1007/s00261-024-04511-5
Verlag, kostenfrei, Volltext: https://link.springer.com/article/10.1007/s00261-024-04511-5
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Author Notes:Friedrich L. Pietsch, Florian Haag, Isabelle Ayx, Freba Grawe, Abhinay K. Vellala, Stefan O. Schoenberg, Matthias F. Froelich, Hishan Tharmaseelan
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Summary:Tumoral heterogeneity poses a challenge for personalized cancer treatments. Especially in metastasized cancer, it remains a major limitation for successful targeted therapy, often leading to drug resistance due to tumoral escape mechanisms. This work explores a non-invasive radiomics-based approach to capture textural heterogeneity in liver lesions and compare it between colorectal cancer (CRC) and pancreatic cancer (PDAC).
Item Description:Online veröffentlicht: 8. August 2024
Gesehen am 05.11.2024
Physical Description:Online Resource
ISSN:2366-0058
DOI:10.1007/s00261-024-04511-5