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Specific chromatin states and m6A modifications are associated with mRNA mobility in planta

An alternative computational model suggests that mRNA mobility may primarily hinge on RNA abundance rather than sequence specificity [2]. Recent research provides an intriguing insight: m5C peaks tend to be concentrated in chromatin regions devoid of the repressive histone mark H3K27me3 [3]. This im...

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Hauptverfasser: Liu, Xiaojun (VerfasserIn) , Uslu, Veli Vural (VerfasserIn) , Chen, Ying (VerfasserIn) , Han, Xiao (VerfasserIn) , Berr, Alexandre (VerfasserIn) , Zhang, Wenna (VerfasserIn) , Dong, Yihan (VerfasserIn)
Dokumenttyp: Article (Journal) Editorial
Sprache:Englisch
Veröffentlicht: 8 April 2024
In: Horticulture research
Year: 2024, Jahrgang: 11, Heft: 6, Pages: 1-4
ISSN:2052-7276
DOI:10.1093/hr/uhae101
Online-Zugang:Verlag, kostenfrei, Volltext: https://doi.org/10.1093/hr/uhae101
Volltext
Verfasserangaben:Xiaojun Li, Veli Vural Uslu, Ying Chen, Xiao Han, Alexandre Berr, Wenna Zhang, and Yihan Dong
Beschreibung
Zusammenfassung:An alternative computational model suggests that mRNA mobility may primarily hinge on RNA abundance rather than sequence specificity [2]. Recent research provides an intriguing insight: m5C peaks tend to be concentrated in chromatin regions devoid of the repressive histone mark H3K27me3 [3]. This implies a positive association between m5C-modified mRNAs and active transcription. In an attempt to reconcile these divergent models, we have revisited experimental data on mobile mRNAs. Our findings suggest a refined perspective, indicating that mobile mRNAs are linked with specific chromatin states and predominantly associated with another RNA epigenetic mark, N6-methyladenosine (m6A) modifications.
Beschreibung:Gesehen am 18.11.2024
Beschreibung:Online Resource
ISSN:2052-7276
DOI:10.1093/hr/uhae101

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