Molecular causality in the advent of foundation models

Correlation is not causation: this simple and uncontroversial statement has far-reaching implications. Defining and applying causality in biomedical research has posed significant challenges to the scientific community. In this perspective, we attempt to connect the partly disparate fields of system...

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Bibliographic Details
Main Authors: Lobentanzer, Sebastian (Author) , Rodriguez Mier, Pablo (Author) , Bauer, Stefan (Author) , Sáez Rodríguez, Julio (Author)
Format: Article (Journal)
Language:English
Published: August 2024
In: Molecular systems biology
Year: 2024, Volume: 20, Issue: 8, Pages: 848-858
ISSN:1744-4292
DOI:10.1038/s44320-024-00041-w
Online Access:Verlag, kostenfrei, Volltext: https://doi.org/10.1038/s44320-024-00041-w
Verlag, kostenfrei, Volltext: https://www.embopress.org/doi/full/10.1038/s44320-024-00041-w
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Author Notes:Sebastian Lobentanzer, Pablo Rodriguez-Mier, Stefan Bauer & Julio Saez-Rodriguez
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Summary:Correlation is not causation: this simple and uncontroversial statement has far-reaching implications. Defining and applying causality in biomedical research has posed significant challenges to the scientific community. In this perspective, we attempt to connect the partly disparate fields of systems biology, causal reasoning, and machine learning to inform future approaches in the field of systems biology and molecular medicine.
Item Description:Online veröffentlicht: 18. Juni 2024
Gesehen am 19.11.2024
Physical Description:Online Resource
ISSN:1744-4292
DOI:10.1038/s44320-024-00041-w