Statins did not reduce the frequency of exacerbations in individuals with COPD and cardiovascular comorbidities in the COSYCONET cohort

The evidence regarding effects of statins on exacerbation risk in COPD remains controversial. Previous studies often excluded patients with cardiovascular comorbidities despite their high prevalence in COPD and role for exacerbations. Based on the cardioprotective properties of statins, we hypothesi...

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Main Authors:	Frantzi, Nikoleta (Author) , Nguyen, Xuan Phuc (Author) , Herr, C. (Author) , Alter, P. (Author) , Söhler, S. (Author) , Soriano, Daniel (Author) , Watz, H. (Author) , Waschki, B. (Author) , Trinkmann, Frederik (Author) , Eichenlaub, M. (Author) , Trudzinski, Franziska (Author) , Michels-Zetsche, Julia D. (Author) , Omlor, A. (Author) , Seiler, F. (Author) , Moneke, I. (Author) , Biertz, F. (Author) , Rohde, G. (Author) , Stolz, Daiana (Author) , Welte, T. (Author) , Kauczor, Hans-Ulrich (Author) , Kahnert, K. (Author) , Jörres, R. A. (Author) , Vogelmeier, C. F. (Author) , Bals, R. (Author) , Fähndrich, S. (Author)
Format:	Article (Journal)
Language:	English
Published:	15 May 2024
In:	Respiratory research Year: 2024, Volume: 25, Pages: 1-12
ISSN:	1465-993X
DOI:	10.1186/s12931-024-02822-1
Online Access:	Verlag, kostenfrei, Volltext: https://doi.org/10.1186/s12931-024-02822-1
Author Notes:	N. Frantzi, X.P. Nguyen, C. Herr, P. Alter, S. Söhler, D. Soriano, H. Watz, B. Waschki, F. Trinkmann, M. Eichenlaub, F.C. Trudzinski, J.D. Michels-Zetsche, A. Omlor, F. Seiler, I. Moneke, F. Biertz, G. Rohde, D. Stolz, T. Welte, H.U. Kauczor, K. Kahnert, R.A. Jörres, C.F. Vogelmeier, R. Bals, S. Fähndrich and on behalf of the German COSYCONET Cohort