A servo-control system for open- and closed-loop blood pressure regulation
An electropneumatic servo-control system is described that can reduce and control arterial blood pressure in experimental animals. The device has been proved useful in the analysis of pressure-dependent physiological processes and allows the following two modes of operation: 1) a conventional open-l...
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| Main Authors: | , , , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
February 1992
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| In: |
American journal of physiology. Renal physiology
Year: 1992, Volume: 262, Issue: 2, Pages: F320-F325 |
| ISSN: | 1522-1466 |
| DOI: | 10.1152/ajprenal.1992.262.2.F320 |
| Online Access: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1152/ajprenal.1992.262.2.F320 Verlag, lizenzpflichtig, Volltext: https://journals.physiology.org/doi/abs/10.1152/ajprenal.1992.262.2.F320 
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| Author Notes: | B. Nafz, P.B. Persson, H. Ehmke, H.R. Kirchheim |
| Summary: | An electropneumatic servo-control system is described that can reduce and control arterial blood pressure in experimental animals. The device has been proved useful in the analysis of pressure-dependent physiological processes and allows the following two modes of operation: 1) a conventional open-loop setting that will reduce arterial pressure to a preselected set point and 2) a closed-loop mode that enables an adjustment to a dynamic pressure set point (i.e., the controlled pressure is reduced to a constant value below a reference pressure). A pneumatic servo-control mechanism was chosen to provide minimal control latency. The accuracy of the system under physiological conditions is well within +/- 1 mmHg. The device can be useful in a number of studies demanding a precise regulation of local arterial pressure, such as experiments on blood flow autoregulation, arterial baroreceptor reflexes, and all experiments involving the study of pressure-dependent excretory and incretory functions of the kidney. The closed-loop setting is useful for studying physiological feedback systems. |
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| Item Description: | Gesehen am 25.11.2025 |
| Physical Description: | Online Resource |
| ISSN: | 1522-1466 |
| DOI: | 10.1152/ajprenal.1992.262.2.F320 |