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Interleukin-6 as a critical inflammatory marker for early diagnosis of surgical site infection after spine surgery: research

Early diagnosis of surgical site infections (SSIs) could prevent surgical revision. Inflammatory markers (IMs), such as procalcitonin (PCT), interleukin-6 (IL-6), and tumor necrosis factor α (TNF-α), seem more accurate in diagnosing SSI than C-reactive protein (CRP) and white blood cell (WBC) count....

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Main Authors: Roch, Paul (Author) , Ecker, Carolin (Author) , Jäckle, Katharina (Author) , Meier, Marc-Pascal (Author) , Reinhold, Maximilian (Author) , Klockner, Friederike Sophie (Author) , Lehmann, Wolfgang (Author) , Weiser, Lukas (Author)
Format: Article (Journal)
Language:English
Published: 6 May 2024
In: Infection
Year: 2024, Volume: 52, Issue: 6, Pages: 2269-2277
ISSN:1439-0973
DOI:10.1007/s15010-024-02271-4
Online Access:Verlag, kostenfrei, Volltext: https://doi.org/10.1007/s15010-024-02271-4
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Author Notes:Paul Jonathan Roch, Carolin Ecker, Katharina Jäckle, Marc-Pascal Meier, Maximilian Reinhold, Friederike Sophie Klockner, Wolfgang Lehmann, Lukas Weiser
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Summary:Early diagnosis of surgical site infections (SSIs) could prevent surgical revision. Inflammatory markers (IMs), such as procalcitonin (PCT), interleukin-6 (IL-6), and tumor necrosis factor α (TNF-α), seem more accurate in diagnosing SSI than C-reactive protein (CRP) and white blood cell (WBC) count. The aim was to compare the predictive values of CRP, WBC count, PCT, IL-6, and TNF-α in SSI detection.
Item Description:Gesehen am 13.01.2025
Physical Description:Online Resource
ISSN:1439-0973
DOI:10.1007/s15010-024-02271-4

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