MethSCAn: accurate exploratory analysis of single-cell methylomes: research briefing
Single-cell bisulfite sequencing enables the genome-wide quantification of DNA methylation at single-cell resolution, but methods to analyze the resulting data are lacking. The MethSCAn software accurately distinguishes cell types and states by scanning the genome for informative regions and providi...
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| Main Author: | |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
September 2024
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| In: |
Nature methods
Year: 2024, Volume: 21, Issue: 9, Pages: 1595-1596 |
| ISSN: | 1548-7105 |
| DOI: | 10.1038/s41592-024-02348-w |
| Online Access: | Verlag, kostenfrei, Volltext: https://doi.org/10.1038/s41592-024-02348-w Verlag, kostenfrei, Volltext: https://www.nature.com/articles/s41592-024-02348-w 
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| Author Notes: | Lukas P.M. Kremer |
| Summary: | Single-cell bisulfite sequencing enables the genome-wide quantification of DNA methylation at single-cell resolution, but methods to analyze the resulting data are lacking. The MethSCAn software accurately distinguishes cell types and states by scanning the genome for informative regions and providing a robust approach to quantifying methylation within these regions. |
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| Item Description: | Veröffentlicht am 31. Juli 2024 Gesehen am 26.11.2024 This is a summary of: Kremer, L. P. M. et al. Analyzing single-cell bisulfite sequencing data with MethSCAn. Nat. Methods https://doi.org/10.1038/s41592-024-02347-x (2024) |
| Physical Description: | Online Resource |
| ISSN: | 1548-7105 |
| DOI: | 10.1038/s41592-024-02348-w |