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Fundus autofluorescence in posterior and panuveitis: an under-estimated imaging technique: a review and case series

Fundus autofluorescence (FAF) is a prompt and non-invasive imaging modality helpful in detecting pathological abnormalities within the retina and the choroid. This narrative review and case series provides an overview on the current application of FAF in posterior and panuveitis. The literature was...

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Main Authors: Mauschitz, Matthias (Author) , Zeller, Markus (Author) , Sagar, Pradeep (Author) , Biswal, Suchitra (Author) , Guzman, Gabriela (Author) , Terheyden, Jan H. (Author) , Meyer, Carsten H. (Author) , Holz, Frank G. (Author) , Heinz, Carsten (Author) , Pleyer, Uwe (Author) , Finger, Robert P. (Author) , Wintergerst, Maximilian W. M. (Author)
Format: Article (Journal)
Language:English
Published: 25 April 2024
In: Biomolecules
Year: 2024, Volume: 14, Issue: 5, Pages: 1-20
ISSN:2218-273X
DOI:10.3390/biom14050515
Online Access:Verlag, kostenfrei, Volltext: https://doi.org/10.3390/biom14050515
Verlag, kostenfrei, Volltext: https://www.mdpi.com/2218-273X/14/5/515
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Author Notes:Matthias M. Mauschitz, Markus Zeller, Pradeep Sagar, Suchitra Biswal, Gabriela Guzman, Jan H. Terheyden, Carsten H. Meyer, Frank G. Holz, Carsten Heinz, Uwe Pleyer, Robert P. Finger and Maximilian W. M. Wintergerst
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Summary:Fundus autofluorescence (FAF) is a prompt and non-invasive imaging modality helpful in detecting pathological abnormalities within the retina and the choroid. This narrative review and case series provides an overview on the current application of FAF in posterior and panuveitis. The literature was reviewed for articles on lesion characteristics on FAF of specific posterior and panuveitis entities as well as benefits and limitations of FAF for diagnosing and monitoring disease. FAF characteristics are described for non-infectious and infectious uveitis forms as well as masquerade syndromes. Dependent on the uveitis entity, FAF is of diagnostic value in detecting disease and following the clinical course. Currently available FAF modalities which differ in excitation wavelengths can provide different pathological insights depending on disease entity and activity. Further studies on the comparison of FAF modalities and their individual value for uveitis diagnosis and monitoring are warranted.
Item Description:Gesehen am 11.12.2024
Physical Description:Online Resource
ISSN:2218-273X
DOI:10.3390/biom14050515

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