Comment on: Portal vein embolization versus dual vein embolization for management of the future liver remnant in patients undergoing major hepatectomy: meta-analysis

The systematic review and meta-analysis by Bell et al.1 is of great interest and they are congratulated for their valuable study. However, the following comments on the results of the study are offered.Bell et al.1 concluded that dual vein embolization was associated with a lower mortality rate comp...

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Main Authors: Oweira, Hani (Author) , Krimi, Bassem (Author) , Gouader, Amine (Author) , Seiller, Ian (Author) , Chaouch, Mohamed Ali (Author)
Format: Article (Journal)
Language:English
Published: August 2024
In: BJS open
Year: 2024, Volume: 8, Issue: 4, Pages: 1-2
ISSN:2474-9842
DOI:10.1093/bjsopen/zrae057
Online Access:Verlag, kostenfrei, Volltext: https://doi.org/10.1093/bjsopen/zrae057
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Author Notes:Hani Oweira, Bassem Krimi, Amine Gouader, Ian Seiller and Mohamed Ali Chaouch
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Summary:The systematic review and meta-analysis by Bell et al.1 is of great interest and they are congratulated for their valuable study. However, the following comments on the results of the study are offered.Bell et al.1 concluded that dual vein embolization was associated with a lower mortality rate compared with portal vein embolization, as depicted in the forest plot in Figure 4 of their article. However, a significant error in this forest plot erroneously altered the direction of the pooled effect size, creating a false impression of a beneficial effect on mortality rates. Specifically, the reported number of events in the two groups from the study by Le Roy et al.2 was inaccurate. The number of mortalities in the dual vein embolization group should be three, not one. Upon re-analysing the data using the fixed-effect model, there is no significant difference between the two groups (OR 0.43, 95% c.i. 0.16 to 1.12; P = 0.080) (Fig. 1), with no heterogeneity among the studies.
Item Description:Veröffentlicht: 4. Juli 2024
Gesehen am 19.12.2024
Physical Description:Online Resource
ISSN:2474-9842
DOI:10.1093/bjsopen/zrae057