Genetic alterations in myeloproliferative and myelodysplastic/myeloproliferative neoplasms: a practical guide to WHO-HAEM5
Within the World Health Organization (WHO) classification of haematopoietic neoplasms, particularly its fifth version from 2022 (WHO-HAEM5), myeloid neoplasms are not only grouped into myeloproliferative (MPN) and myelodysplastic neoplasms (MDS). There is also a group of haematological disorders tha...
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| Main Authors: | , , , , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
6. März 2024
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| In: |
Medizinische Genetik
Year: 2024, Volume: 36, Issue: 1, Pages: 31-38 |
| ISSN: | 1863-5490 |
| DOI: | 10.1515/medgen-2024-2003 |
| Online Access: | Verlag, kostenfrei, Volltext: https://doi.org/10.1515/medgen-2024-2003 Verlag, kostenfrei, Volltext: https://www.degruyterbrill.com/document/doi/10.1515/medgen-2024-2003/html |
| Author Notes: | Constanze Kühn, Katharina Hörst, Hans M. Kvasnicka, Andreas Hochhaus, Andreas Reiter |
| Summary: | Within the World Health Organization (WHO) classification of haematopoietic neoplasms, particularly its fifth version from 2022 (WHO-HAEM5), myeloid neoplasms are not only grouped into myeloproliferative (MPN) and myelodysplastic neoplasms (MDS). There is also a group of haematological disorders that share features of both categories termed myelodysplastic /myeloproliferative neoplasms (MDS/MPN). In this article, we aim to provide a comprehensive and practical guide to WHO-HAEM5 highlighting the genetic alterations that underlie MPN and MDS/MPN. This guide provides an overview of the overlapping commonalities among these entities, as well as their unique characteristics. |
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| Item Description: | Gesehen am 08.01.2025 |
| Physical Description: | Online Resource |
| ISSN: | 1863-5490 |
| DOI: | 10.1515/medgen-2024-2003 |