Cover Image

Morbus Dupuytren: Epidemiologie, Diagnose, Therapie, Outcome : CME : zertifizierte Fortbildung

Dupuytren’s contracture is a fibroproliferative systemic disease that cannot be stopped by medication. The overall prevalence is 7-8%. Men are affected 3-4 times more frequently. The cause of the disease is not known. A genetic disposition and thus familial clustering are being discussed. Risk facto...

Full description

Saved in:
Bibliographic Details
Main Authors: Harbrecht, Andreas (Author) , Honigmann, Philipp (Author) , Löw, Steffen (Author) , Müller, Lars Peter (Author) , Unglaub, Frank (Author) , Spies, Christian (Author)
Format: Article (Journal)
Language:German
Published: November 2024
In: Die Orthopädie
Year: 2024, Volume: 53, Issue: 11, Pages: 893-902
ISSN:2731-7153
DOI:10.1007/s00132-024-04553-z
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1007/s00132-024-04553-z
Verlag, lizenzpflichtig, Volltext: http://link.springer.com/article/10.1007/s00132-024-04553-z
Get full text
Author Notes:A. Harbrecht, P. Honigmann, S. Löw, L.P. Müller, F. Unglaub, C.K. Spies
Description
Summary:Dupuytren’s contracture is a fibroproliferative systemic disease that cannot be stopped by medication. The overall prevalence is 7-8%. Men are affected 3-4 times more frequently. The cause of the disease is not known. A genetic disposition and thus familial clustering are being discussed. Risk factors for the development of a Dupuytren’s contracture are work-related stress (microtrauma), nicotine and alcohol consumption, epilepsy and diabetes mellitus as well as advanced age. The prognosis is poor in cases with a positive family history, bilateral involvement, age <50 years and male gender. Several treatment options are available. Conservative therapy has no lasting benefit. Minimally invasive procedures include partial needle aponeurectomy or the injection of collagenase. Surgical procedures range from partial aponeurectomy to dermatoaponeurectomy. The recurrence risk of the gold standard treatment of surgery (partial aponeurectomy) is 20.9%.
Item Description:Online publiziert: 25. September 2024
Gesehen am 20.01.2025
Physical Description:Online Resource
ISSN:2731-7153
DOI:10.1007/s00132-024-04553-z

Similar Items