Characteristics of H3K27M-mutant diffuse gliomas with a non-midline location
Diffuse midline gliomas (DMG) with H3K27 alterations (H3K27M-DMG) are a highly aggressive form of brain cancer. In rare cases, H3K27 mutations have been observed in diffuse non-midline gliomas (DNMG). It is currently unclear how these tumors should be classified. Herein, we analyze the characteristi...
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| Main Authors: | , , , , , , , , , , , , , , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
27 June 2024
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| In: |
Journal of neuro-oncology
Year: 2024, Volume: 169, Issue: 2, Pages: 391-398 |
| ISSN: | 1573-7373 |
| DOI: | 10.1007/s11060-024-04733-z |
| Online Access: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1007/s11060-024-04733-z |
| Author Notes: | Souhir Guidara, Antoine Seyve, Delphine Poncet, Camille Leonce, Pierre-Paul Bringuier, Anne McLeer, Dominik Sturm, Stéphanie Cartalat, Thiebaud Picart, Anthony Ferrari, Jürgen Hench, Stephan Frank, David Meyronet, François Ducray, Marc Barritault |
| Summary: | Diffuse midline gliomas (DMG) with H3K27 alterations (H3K27M-DMG) are a highly aggressive form of brain cancer. In rare cases, H3K27 mutations have been observed in diffuse non-midline gliomas (DNMG). It is currently unclear how these tumors should be classified. Herein, we analyze the characteristics of DNMG with H3K27M mutations. |
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| Item Description: | Gesehen am 24.01.2025 |
| Physical Description: | Online Resource |
| ISSN: | 1573-7373 |
| DOI: | 10.1007/s11060-024-04733-z |