Cover Image

A baseline for machine-learning-based hepatocellular carcinoma diagnosis using multi-modal clinical data

The objective of this paper is to provide a baseline for performing multi-modal data classification on a novel open multimodal dataset of hepatocellular carcinoma (HCC), which includes both image data (contrast-enhanced CT and MRI images) and tabular data (the clinical laboratory test data as well a...

Full description

Saved in:
Bibliographic Details
Main Authors: Wang, Binwu (Author) , Rodriguez, Isaac (Author) , Breitinger, Leon (Author) , Tollens, Fabian (Author) , Itzel, Timo (Author) , Grimm, Dennis (Author) , Sirazitdinov, Andrei (Author) , Froelich, Matthias F. (Author) , Schönberg, Stefan (Author) , Teufel, Andreas (Author) , Hesser, Jürgen (Author) , Zhao, Wenzhao (Author)
Format: Article (Journal) Chapter/Article
Language:English
Published: 20 Jan 2025
In: Arxiv
Year: 2025, Pages: 1-7
DOI:10.48550/arXiv.2501.11535
Online Access:Verlag, kostenfrei, Volltext: https://doi.org/10.48550/arXiv.2501.11535
Verlag, kostenfrei, Volltext: http://arxiv.org/abs/2501.11535
Get full text
Author Notes:Binwu Wang, Isaac Rodriguez, Leon Breitinger, Fabian Tollens, Timo Itzel, Dennis Grimm, Andrei Sirazitdinov, Matthias Frölich, Stefan Schönberg, Andreas Teufel, Jürgen Hesser, Wenzhao Zhao
Description
Summary:The objective of this paper is to provide a baseline for performing multi-modal data classification on a novel open multimodal dataset of hepatocellular carcinoma (HCC), which includes both image data (contrast-enhanced CT and MRI images) and tabular data (the clinical laboratory test data as well as case report forms). TNM staging is the classification task. Features from the vectorized preprocessed tabular data and radiomics features from contrast-enhanced CT and MRI images are collected. Feature selection is performed based on mutual information. An XGBoost classifier predicts the TNM staging and it shows a prediction accuracy of $0.89 \pm 0.05$ and an AUC of $0.93 \pm 0.03$. The classifier shows that this high level of prediction accuracy can only be obtained by combining image and clinical laboratory data and therefore is a good example case where multi-model classification is mandatory to achieve accurate results.
Item Description:Gesehen am 10.02.2025
Physical Description:Online Resource
DOI:10.48550/arXiv.2501.11535

Similar Items