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Impact of different parametric Patlak imaging approaches and comparison with a 2-tissue compartment pharmacokinetic model with a long axial field-of-view (LAFOV) PET/CT in oncological patients

The recently introduced Long-Axial-Field-of-View (LAFOV) PET-CT scanners allow for the first-time whole-body dynamic- and parametric imaging. Primary aim of this study was the comparison of direct and indirect Patlak imaging as well as the comparison of different time frames for Patlak calculation w...

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Bibliographische Detailangaben
Hauptverfasser: Pan, Leyun (VerfasserIn) , Sachpekidis, Christos (VerfasserIn) , Hassel, Jessica C. (VerfasserIn) , Christopoulos, Petros (VerfasserIn) , Dimitrakopoulou-Strauss, Antonia (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: 2025
In: European journal of nuclear medicine and molecular imaging
Year: 2025, Jahrgang: 52, Heft: 2, Pages: 623-637
ISSN:1619-7089
DOI:10.1007/s00259-024-06879-4
Online-Zugang:Verlag, kostenfrei, Volltext: https://doi.org/10.1007/s00259-024-06879-4
Volltext
Verfasserangaben:Leyun Pan, Christos Sachpekidis, Jessica Hassel, Petros Christopoulos, Antonia Dimitrakopoulou-Strauss
Beschreibung
Zusammenfassung:The recently introduced Long-Axial-Field-of-View (LAFOV) PET-CT scanners allow for the first-time whole-body dynamic- and parametric imaging. Primary aim of this study was the comparison of direct and indirect Patlak imaging as well as the comparison of different time frames for Patlak calculation with the LAFOV PET-CT in oncological patients. Secondary aims of the study were lesion detectability and comparison of Patlak analysis with a two-tissue-compartment model (2TCM).
Beschreibung:Gesehen am 17.02.2025
Beschreibung:Online Resource
ISSN:1619-7089
DOI:10.1007/s00259-024-06879-4

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