Association of lysophosphatidic acids with cerebrospinal fluid biomarkers and progression to Alzheimer’s disease

Lysophosphatidic acids (LPAs) are bioactive signaling phospholipids that have been implicated in Alzheimer’s disease (AD). It is largely unknown whether LPAs are associated with AD pathology and progression from mild cognitive impairment (MCI) to AD.

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Bibliographic Details
Main Authors: Ahmad, Shahzad (Author) , Orellana, Adelina (Author) , Kohler, Isabelle (Author) , Frölich, Lutz (Author) , de Rojas, Itziar (Author) , Gil, Silvia (Author) , Boada, Mercè (Author) , Hernández, Isabel (Author) , Hausner, Lucrezia (Author) , Bakker, Margot H. M. (Author) , Cabrera-Socorro, Alfredo (Author) , Amin, Najaf (Author) , Ramírez, Alfredo (Author) , Ruiz, Agustín (Author) , Hankemeier, Thomas (Author) , Van Duijn, Cornelia M. (Author)
Format: Article (Journal)
Language:English
Published: 02 October 2020
In: Alzheimer's research & therapy
Year: 2024, Volume: 12, Pages: 1-13
ISSN:1758-9193
DOI:10.1186/s13195-020-00680-9
Online Access:Verlag, kostenfrei, Volltext: https://doi.org/10.1186/s13195-020-00680-9
Verlag, kostenfrei, Volltext: https://alzres.biomedcentral.com/articles/10.1186/s13195-020-00680-9
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Author Notes:Shahzad Ahmad, Adelina Orellana, Isabelle Kohler, Lutz Frölich, Itziar de Rojas, Silvia Gil, Mercè Boada, Isabel Hernández, Lucrezia Hausner, Margot H.M. Bakker, Alfredo Cabrera-Socorro, Najaf Amin, Alfredo Ramírez, Agustín Ruiz, Thomas Hankemeier and Cornelia M. Van Duijn
Description
Summary:Lysophosphatidic acids (LPAs) are bioactive signaling phospholipids that have been implicated in Alzheimer’s disease (AD). It is largely unknown whether LPAs are associated with AD pathology and progression from mild cognitive impairment (MCI) to AD.
Item Description:Gesehen am 24.03.2025
Physical Description:Online Resource
ISSN:1758-9193
DOI:10.1186/s13195-020-00680-9